DreINT0009060 @ danRer10
Intron Retention
Gene
ENSDARG00000074914 | DMPK
Description
dystrophia myotonica-protein kinase [Source:HGNC Symbol;Acc:HGNC:2933]
Coordinates
chr10:363254-364092:-
Coord C1 exon
chr10:363999-364092
Coord A exon
chr10:363452-363998
Coord C2 exon
chr10:363254-363451
Length
547 bp
Sequences
Splice sites
5' ss Seq
CTGGTGAAG
5' ss Score
2.39
3' ss Seq
AGGTGTGTGTGTTCTGACAGGTG
3' ss Score
9.5
Exon sequences
Seq C1 exon
AGATATTAAACCTGACAATATCCTGCTGACGGCAGACGGCCACGCACGGCTCGGGGATTTCGGCTCATGTCTCCGGCTAGAAGATGATGGACTG
Seq A exon
GTGAAGTTTTATTCTGGGCCTGTACCACAATGCTGGCTTAATAAACTCAGAGTTGCAGGATTAGTTTCCAGTTGAAAGAACCAAACCATTGCAGTCAGGGTTTATTGGTACCATTAAGATTTCTCTGTTAATTCCAGCTTAATTTTCTTTTTTTAAATTCTTTTGTTTATTATTCTCCTTAATTTAGTTTGTGAGCATGAGCAAATAAAGGCAGGAGTTCTGGAGTTATATTTATGCCACAATTCTGTGCACAAAATTTTAAATGTGTGCAAAATGACTTGACTTTATGCTTTAGTTTAGTCTTTAGTTTTTTGTGGTCCCATTTGTGTGCATGCAACATCACCCGACTTGTGCACAAAAGTAACCTCAATACTGAGTTTACACAACATGCCATTTTGAATATAAAAAGAGCATAACTTGAACACTCATGCTAACATCATGGTAGCTAAAACCCAGAATTGGTGTGAACTAAACTGAAAGTTATCCACCAGCTAATCTAGCTGCATGGCGTAGGCACAGATGTGCTCAGGTGTGTGTGTTCTGACAG
Seq C2 exon
GTGCACTCGGCGGTGGCGGTCGGGACTCCAGATTATCTGTCTCCAGAACTCCTGCGGGCGGTGGAGGCTGGTGGGGGATACGGATCTGACTGCGACTGGTGGGCTCTAGGCGTCTGCGCATATGAGATGCTGCTGGGAACCACACCGTTCTATGCAGAGTCCATCTCTGAGACCTACGCCAAAATCATTCACTTCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000074914:ENSDART00000114487:6
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=FE(13.2=100)
A:
NA
C2:
PF0006920=Pkinase=FE(27.8=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TAAACCTGACAATATCCTGCTGACG
R:
CTTGAAGTGAATGATTTTGGCGT
Band lengths:
286-833
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]