DreINT0086992 @ danRer10
Intron Retention
Gene
ENSDARG00000078475 | klhl23
Description
kelch-like family member 23 [Source:ZFIN;Acc:ZDB-GENE-081104-458]
Coordinates
chr9:48477436-48481841:-
Coord C1 exon
chr9:48480629-48481841
Coord A exon
chr9:48477589-48480628
Coord C2 exon
chr9:48477436-48477588
Length
3040 bp
Sequences
Splice sites
5' ss Seq
AAGGTATGA
5' ss Score
9.11
3' ss Seq
TTTTATTATTTATTTTAAAGGTG
3' ss Score
9.24
Exon sequences
Seq C1 exon
ATGTCCGGGAATGCTCAAAGCGGTTACTCCTACGACTTCTACGATGCCTCTCACCCTTCAGAAGTGCTTGAAGCTCTTCACGAGTTTCACAACAGCGGCCTGTTCACCGACATCGCCCTGCAGTCCTCATCGGGACAGCTCTTCCACTGCCACAAAGCCGTCCTATCAGCGCGCAGCTCCTATTTCAAAGTAATGTTCACCTTAGACATGAGAGAACGTGCGAACGACACCATCAACCTACCTTGCGTAGACGGAGAAATTTTGGGTGCTTTGGTGACCTACGTGTACACCGCCAAAATCGGCATAACTCAAAACAACGTACAACGTCTACTGGAGGCCGCAGACCTGCTGCAGTTCAACTCGCTCAAGAAAGCCTGCGAAAACTTTTTGATTCGTCTGCTAGATGTTGATAATTGCCTCGGGATGCATTCGTTCGCTGAGCTTCATGTTTGTTCAGCATTGGAAAGAGCGGCTTTGAGGATCATCCTGAGTCGTTTTGAAGACGTCACGCTTCAGGATGAATTCCCAGAGACCGGTTTTCAAAAGCTGATGGCGATTTTATCAACAGAGAACCTAAATGTGTGGAAAGACACAACGTTATTGGATGCGGTCGTGAAATGGGTCGTTTATGACGTAGCTTCTCGAATTGATCACATTCAAGAGCTCCTCAACTGCATTCATATTAACGTAGACGATGTTTATCTGAAAATGGCGTTAGATCTGCGCAAATGTTGCTCTGAGAGCAAACTGAGATCTTTAATTCTGACCTCCTTGAAACCAAGTAAAGGTTTTTCAGACTGTTGCAAGAAGCCGACATGCAGTTTGTATGTTATCGGTGGATATTATTGGCATCCTTTGTGCGAAGTTCACATGTGGGACCCCGTTTCCAACACGTGGGTTCAGGGAAAAGACATGCCTGATTTTGCAAGGGAGAGCTATAGTGTGGTTCTTCTAGGGGCTGATATTTATGTGACCGGAGGGTACAGGACAGAGACTGTCGATGCTTTAGATAATGTGTGGATTTATAATACAGATTCAGATGAATGGACTGAAGGATGTCCGATGATCACAGCTAGGTATTATCACTGCTCTGTGGCGTTACGTGGATGTGTATATGTGATAGGTGGATATACAGCAGGCGCTCCTACTCAAGAAACTGAATTTTATGATCCTTTGAAGAAGACTTGGTTTCCGGTGGCTGAAATGATACAAG
Seq A exon
GTATGAGAAATTATGTTTATTATCTTTTATTCATTCGTTTTCTTGAGCAGAATGAACAGCCAACTTATCCAGCAAGTTTTTATGCAGCGACAGCAGATTCCAGCCACAACCCATCTGTGGGAAACATCCACACACACTCTCATACACTATAGACAATTTAGCCTATAGTACACCTGTACCACATGTCTTTGGACTGTGGGGGAAACCGGAGCACCCGGAGGAAACCCACACGAAGGCAGGGAGAAACGCCAACTGAGCCGAGGTTCAAACCAGCGACCCAGCGACCTTCTTGCTGTGAGGCGACAGCACTACCTATTGCACCACTGCCTCACCCCTTCCTTCGGCTTAGTGCCTTATTTATCAGGGGTCGCCAGAGCAGAATGAACCACCAGCTATTCTAGCATATGTTTTACGCAGCGGATGCCCTTCCAGCCACAACCCACTACTGAAAAACACACAAAGACTCTCACATTCAATCATACTTGTACTCTATGGGTAATTTAGTTAATCGAATTCACCTATAGCACATTTCCTATAGAGGAGGAAACACACGACTATGGGGAGTACATGCAAACTTTACACAGAAATGCTACGTGCTTGCTGTGAGGCAACTGTGCTAACTACTAAGCCACTGTGTTGCCCCATGTTTATTATGAAGCTACTTTATTTTTGTTATTTTAAATTGTAAATATGTAAATGAAAAAAAAAAAGATCCGCATATAACTGCGCATAAAAATACATGTAATAAACAAAATATAGGAATACAGGAGGGTGTTAAATAAAACATAATAATAATAATAATAATAATGACAACAACAATAATAATAGTAGAAGTAAAAAAGAATAAACTAAAGAATAAATGACAGTGATATATTAAAGTATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTAGGGGTGTAATGGTTCACAAAAATCACGGTTCGATACGATACGATACAGTGGTGTTACAGTGGTGTCACGGTTCGGTACATTTTCGATACAGCAAAAAAAGAAAAAAGCCAGTGGATTTCTCTGATTTAATTTTTTTAATGTATTAAAACTAACATCATAAAAGTATGATCCTGTTTTGTTTTCTTTTACTTTAAACAGTGATAGAGCTATATTTCCGGGGTTTCTGCTTAGCAGCAAATAAAAAAAATCCTTCTTTATACTCAAAACCAAAAAGCTGCTTATAAAAAATATAATATTGTAGCAGCTAAACAAATAAAAAGAAAAGAATAATTTAGTTTTTATATGGAGCTCAGTTTCAACCTATTTTCAAGTATTTCTTTATTTTCAGAAAGAGGAGTGTCCACCTTTTCCTCAGACAGCACAGATCTGCTTGATTTGACGGTCATCTGCCATTTTAGTGGATCTGAAAGCAGGAATTATCTGACCGAAATGGGCTTATGAAGGAATAATGTAACGGGGCTCTATTACATTTAACATTTTCTTAAAACCCGACATATTCACTACCGATTAGGATCTCTCAGATCATTTTTTTTCCACCACTCTCTTGGTAGCGGTGATGGTGCGCGACTTATCTGAAGAGCGGTGGAGGCGTGTGCGTGCGATGTACCTGAGTGGTGAGGGTAAGTTGTGCCCAATGTACCTGAAGAGCTGGGAGGGATGCAGTGGAGAGGACCGGGTGGAGACGCGCGATTTCCAGAAGAGTATCTTTCGTTTGCGGTCATCCAGGAGTCTCCCGAAGCTTCCGGGGGTCCAGGGTTGCTGGGGCAATGGGGGCGGAGCCAGCACAAGCAGTTAGGCTGACACAGAAGCTAGCAAGATTGCTAATGAGTGCATGCTTTAATAAAGTCATATTCTGAGTTCAAAAGTGATACTCTACTGTTTAACATGACAGCAGGGAAGGCAGCTTGTTGTCTGCCACGTCATTTGGGATGCCATGTTGAGCGTTGTTGCACTGCAAACATTATTTTTTGTACTTATTCCCTTTTATCTTTTTAGATATTAGTGTAAATTGAATCGTTTGGTTCGTAATGCGTACCGAACCAAAAGTCTCATTCCGAACGGTTTGATACGAATACGCGTATCGTTACACCCTATATACACACACATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATATTACACCAATAGAGAACATTTTTATTATTTTATTTTGAAATTATGCGAACAAAGAAATATGACGTAGACGATCAGCATATAACGGTGAGCATAACAACATGCATGTAATAAACAAAATACAGAAAAACAGGAGGTTGTTAAATAATAATATTAATAATAATGCCAACAACAGCAATAATAAAAGAACAAATAAAAAGGATAAACTAACATACATATTCTACACCGATAAAGAGCAAATTTCTATTATTTTGTTTTGAAATATGTGTGACATATAAAGAAATATGACATGATAGATGAACATAAAATGGTGAGCATAAAAATACCTGTGATAAACAAAATACAGGAATACAGGTGGTTGTTAAATAAATATATTAATAATGATAATGATAATAATAATGCGGGTCTCTCCATACCATCACCAGTGTGTAGCATCCACTTGGATGATGTAGATGATTTAGTGCAAATAATTTTACAGTTGAATGCACTTTATTATATAACTTTATTTGAAATATTCCACAATATATATTGTAGGAATTTCAATAAATAGTTAAATATAAAGCCATTTAACAAATTTACCAGGTATAAGATCAATGGCAACATAACATTAGCATAAAAGAGGCAAATCTGTATTTTAAATTGCATTTAATTTACATACAAATATGTGGAAATTAATATCGTTATTCTACAAAAAATAAAAATAACACTGTTATTTTTAAATTGAAAAAAAATGTTTCATAATATTACAGTTTGTTTTGTATGTCTGATTAAATAATTGGAGCTTTGTGAGCATTTAAAAAAATTAACAAATTTGAGAAATATGTCTTTTATTATTTATTTTAAAG
Seq C2 exon
GTGTGGGAAACGCAACCGCTTGTGTGGTGAATGACAGAGTATATGTAACTGGAGGGCATTATGGGTACAGAGGAACCTGCACTTATGAGAAGATTCAGACTTACAGGCCAGACATCAATGAGTGGAGCATCACAACAATCTGTCCACATCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000078475:ENSDART00000114463:1
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0065126=BTB=WD(100=26.9),PF0770710=BACK=WD(100=24.9),PF0134420=Kelch_1=WD(100=8.1),PF0134420=Kelch_1=WD(100=11.9),PF0134420=Kelch_1=WD(100=11.4),PF0764610=Kelch_2=PU(0.1=0.0)
A:
NA
C2:
PF0764610=Kelch_2=WD(100=90.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]