HsaINT0088698 @ hg19
Intron Retention
Gene
ENSG00000213160 | KLHL23
Description
kelch-like 23 (Drosophila) [Source:HGNC Symbol;Acc:27506]
Coordinates
chr2:170591523-170598047:+
Coord C1 exon
chr2:170591523-170592737
Coord A exon
chr2:170592738-170597894
Coord C2 exon
chr2:170597895-170598047
Length
5157 bp
Sequences
Splice sites
5' ss Seq
AAGGTAAGT
5' ss Score
11
3' ss Seq
TGATTTTAATTAATACGTAGGTG
3' ss Score
5.67
Exon sequences
Seq C1 exon
CCATGGCTCTAAAAGGACAAGAAGATTATATTTATCTTTTCAAGGATTCAACACATCCAGTGGATTTTCTGGATGCATTCAGAACATTTTACTTGGATGGATTATTTACTGATATTACTCTTCAGTGTCCTTCAGGCATAATTTTCCATTGTCACCGAGCCGTTTTAGCTGCTTGCAGCAATTATTTTAAGGCAATGTTCACAGCTGACATGAAAGAAAAATTTAAAAATAAAATAAAACTCTCTGGCATCCACCATGATATTCTGGAAGGCCTTGTAAATTATGCATACACTTCCCAAATTGAAATAACTAAAAGAAATGTTCAAAGCCTGCTTGAGGCAGCGGATCTGCTACAGTTCCTTTCAGTAAAGAAGGCTTGTGAGCGGTTTTTGGTAAGGCACTTGGATATTGATAATTGTATTGGAATGCACTCCTTTGCAGAATTTCATGTGTGTCCAGAACTAGAGAAGGAATCTCGAAGAATTCTATGTTCAAAGTTTAAGGAAGTGTGGCAACAAGAAGAATTTCTGGAAATCAGCCTTGAAAAGTTTCTCTTTATCTTGTCCAGAAAGAATCTCAGTGTTTGGAAAGAAGAAGCTATCATAGAGCCAGTTATTAAGTGGACTGCTCATGATGTAGAAAATCGAATTGAATGCCTCTATAATCTACTGAGCTATATCAACATTGATATAGATCCAGTGTACTTAAAAACAGCCTTAGGCCTTCAAAGAAGCTGCCTGCTCACCGAAAATAAGATCCGCTCCCTAATATACAATGCCTTGAATCCCATGCATAAAGAGATTTCCCAGAGGTCCACAGCCACAATGTATATAATTGGAGGCTATTACTGGCATCCTTTATCAGAGGTTCACATATGGGATCCTTTGACAAATGTTTGGATTCAGGGAGCAGAAATACCAGATTATACCAGGGAGAGCTATGGTGTTACATGTTTAGGACCCAACATTTATGTAACTGGGGGCTACAGGACGGATAACATAGAAGCTCTTGACACAGTGTGGATCTATAACAGTGAAAGTGATGAATGGACAGAAGGTTTGCCAATGCTCAATGCCAGGTATTACCACTGTGCAGTCACCTTGGGTGGCTGTGTCTATGCTTTAGGTGGTTACAGAAAAGGGGCTCCAGCAGAAGAGGCTGAGTTCTATGATCCTTTAAAAGAGAAATGGATTCCTATTGCAAACATGATTAAAG
Seq A exon
GTAAGTGGAGATTATGTTTATTTTGTATTTTTTAGATGTCTGGAGCTAGGCCAGCAGTCTCACTTCTCTTGAATTTATCACTTTGGGATGCTATCTAGGAACTATAGTTAATTATACAAATAATGCTACACAGAATGTTCCAGATAAAAACAGTATAGCATAGTTCCCAACTTGTCTGAGAGTTATGAGAATTTATATTCAAGTCAAGGGCTAGATGAAGAGACAAATCTGGACAGTTTTTCATTTTTTCATGTTCTTAAAATTGAACCCTTTAAAATTCTGCTATTCAACTTTTTCCTCTCAAAATACGCTGATCAGCTCTCAAGAGGTCCTTCATTAAAACCTTGGAAGGTTTGGTCCCTACAGGATGTAACAAAGTACATTCTTCCAGGAACTAGAGACAACGTCTGCTTTTGCAATTCAGTCCTCTCTGAGAGGGGCAGACACCATACTCTCCCTCATGTGGCCCACAGAACCCGGCACACCCCTGGGTCTCGGTATCTGTCTGATAAACACTATTTTCTGCTGTGTTTGGCGATTTGTTTGCCTTGCTCTCCTTCTCTCCCACTGGAAAAAAAGTTAAACGGGAATCTTATTTCATTGTATTTATTCATTGGTGCTGAGGAGTTGTACAAAAACAACTGGTAGGTCGTTACCAAATTTGTATCATTTTGTCCCAAATGTTTCTTCCCAGGCTTTTCTGTTTCTTTTTTAATGCTAGTGAGAGTGTGGGAATTTGACCTGGTCTGGAAATCTGACCTGGTATGATCCTTGGATGACAGGCAGGAAGCTGAGAGGCAGAACAGTCTTGGGATCAGGCACGCTGCCTCTGAAGCTAAACTGCCTGCATCCAGATCCCTGCTTTCCTCTTACTTGCTGATGAGCTCTGGCAAATTGTTTAATCACCCTGTGCCCCCGTTTTGTCATCTGTATAATGGGGATGACAATATTACCTAGTCTCGGATCATTGAGAGGATTAAATTAATCTATGCTTGTGAAGTGCCTAGAACAGTGTCTGACACAGAGTAAGCATGCTATAAATGTTACGCATGATTGTCCTGAATGTCGGTATTGAAGGACATGTCAGCTCTTATAGAGCAGAAATTGATTTCATGTGAAGTTGTGACCACTGTCACACCAGGGTGGGAGAAGGTAGCAGAAAGCCCGGTGCTGTTGCTCCCCTGGTTTTTGTCTTTGCCTGAGTCTCACCACTACTTGCCGATTCCAGGAGGGCTCTGAATGTCCTGACCCCTCTTCTGCAAAAGAAATAAGAAAAGTCCATATATTTAAGGAGCTATTGTAAACTAGCATACATTTCTGATTCTGTTTTTTAAGGATGATATAACAGTTTCAATGGTTTTGTGGTTCAGAGTATATTTCTTTTTCTTTTTCTTTTTTTTTTTTTGAGATGGAGTCTCACTCTGTCTCCCAGGCTGGAATGCAGTGGCGTGATCTTGGCTCACTGCAACCTCTGCCTCCCGGGTTCAAGCAGTTCTCCTGCCTCAGCCTCCTGAGTAGCTGGGATTACAGGCATGTGCCACCACACCTAGGTAATTTTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGCTGGTCTTGAACTCCTGACCTCAAGTGATCCCCCCACCTTGGCCTCCCAAAGTGCTGGGATTACAAGGGTGGGTTCAGAGTATATTTCTTTGAGAATGAAAGCTTATTACTTTACTGAAATTTTAAAAATTTATATTTAGAACAGTGCTTGTTGAAAAAAGATATGCTGCGATGGTGTATCTACTGTGAAACAAAAGCCATATGCATGCTTGCGTTAACCTTGAGTGGAGTAGGAGACCCTCATACCTCAAAGTCCTCCCTCACCTGCTAACTGGGTCTGAAATTCCAGTTTTATACTTTGAACTCAAAGCTTTGATTCTTGTTTATATCTAGTCATCCCAGGGAGAGGTAACACTGCCAGTTATGTGCAGTTTTGACTACTGCTTGTTTTGGTGGGTGGACTCATACAGAACTTTTTTTAAACAATTTTTAAAATTTTATTTTTAATTTTTAAAACTAGAAATGGCGGGGGGTCTCACTATGTTGCCCAGGCTGGTCTTGAACCCCTGGCCTCAAATGATTCTCCTACCTTGGCCTCCCAAAGTGCGGGGATTATAGGTGTGAACCACCACACCCAGCCATACTGAACTTTTAGATTCCCATTTTTTGGTAGAAAGGATAACATTTTTTTCAATTCGTTTTATTTTGTAGCCTTGAAGTGAAATAGCAGCTTTCTCTGGTAATAAACTTAATTTGGGTACAGTCAAATTTAAAATTTATTACCTTTTTTTGGTCCTGGACCCAAATTAAGTTCACTAATGTACAGAGAATAAATAAATACTTGGCTGTTTAGGAACTCCTGAATCTTTATTTTTTTCCATCATAACTGCTCTACTTATAAATCCACTTTTATTTTGGAATAGAAAGGAACAAGAAGATTGAACTGTATCATGCAAAATGGTGCTAGGTAAAAGTTAGTGGAAAGACAAAACCAACGTTTTCAACTAAAATGATCCTCATCATCTTTCTTCCTTTCTTCATCTTCCCTCCAAACCTATTTCCTCCCCCTCCTCCCCCTCCCCTTCCTCACCCTCCCCTCTCTTCCCCCTTCCCCTCCCTCTCCTCCCTATCTCCCTTTCATGTTTCGCCTATCTTCCTCTTTCTTCCTCCTCCTTCCCTCTCCTCCCCCTCCTCCCTCTCCTCCCCCTTCCCCTCCCCCTCCCCCTCCTCCCCTTCCCCTCCCCCATCTCCTCTCCCTCCTTCTGCCTTCTTCTTCCTCCTCCTCCTTCCCCTCCCTCTCCTTCCCCTCCTCGACTTCCCCCACCCCTCCTTGTTTTGGCATCAGTGATTCCAGTTTTTCCAGCTCAGGACCTCAAAATCGGTTTGGTTTGCCTCTGCGTCAGTCAGTCATCAAGACCTGTGTGTTTTACCTGTCTCTTTCCTCTATGCTCTTCCCTCCATACCCAAAGCCCCTTCAAAATCAGGCCCTCGAGACCGCCCACCCTGGCCAGTAACTAGATCTTTCTGGTACCTGTTCTTCCTTTGTTAGTTGCTCTATTCCTCTGTTTAAAAACCTTTAAAATCTGGCTGAATTAAATCCAGATTCTTTGTTGGGCATCAGTAAGTATCCTTTGCTACATGGCTTCAACTTACCATGCCAGCCTTAAAGTCCCATGCAACAACCCTCAATGTGCCACCTGCCCTGGTCAAACTGGGCTACTTAACATTGTCCAGTAAGCCTTTGCACTGGCTTTTCCCTCTGTCTAGAATGGCCTCCTCTCATCTATACTTGCCAACTTCCTACCATCACCCAGGTCAAATTCCACCACCACCTGCTGTGATTTCCCTCGTCAAATGCAGTGTTTTCTTGCCCTGACCATGCCCAGCAGTTCATCTGTCCCTTTTTTCATGGTGTTTCTTCCATTTTATATCTAGTGTTCTAATTACAGCCATGTGCCACTTAACAATGGGGATATGTTCTGAGAAATGTGTGATTAGGCAATTTTGTCATGTGAACGTTATACTTAAACAACAGGCTATACCATACTAATTCTACAGCCTAATACACACCTAGGCTGTGTGGTATAGCCTGTTACTCCTAGGCTTCAGACCTGTACAGCATGTTACTATACTGAATATTCTAAGCAGTATAACACAATGGTAAGTCTTTGTGTATCTAAACATAGAAACAGTACAGTAAAAATACAGCATAAAAGATAAAAATGGTAGACCTATTTGGGGCACTTACCATGAATGGAGCTTGCAGGACTGGAAGTTGTTCTGGTTGAGTCGGTGAGTAAGTGGGGAGGGATTGTGAAGGCCTAGGACATTACTGTACACTACTGTAGACTTTTTACTTTTTTTGAGACAGGGTCTTGCTCTGACACGTACGCTGGACTGCGGTGATGTAAACATAGCTCACTGCAGCCTTGACCTCCTGAGATCAAGCAATCCTCCCACCTCAGCCTCCCGAGTAGCTGGGACTACAGGCACATGCTATCACACGTGGCTACTTTTTTATTTTTTGTAGAGATGTGGTCTCACTTTGTAGTCCAAGCTGGTCTCAAACTCCTCCTGGGCTCAAGTGATCCCCTGCCTCAGCCTCCTAAACTTCTGGAATTACAGGCATTACTGTAGACTTTATATAGCTTATAAAAATACTTTCTTTTTATCCTTATTCTATAAGCTTTTTTTTTTTTTGAGACGGAGTCTCGCTCTGTCACCCAGGCTGGAGTGCAGTGGCACTGTCTTGGCTCACTGCAAGCTCAGTCTCCTGGGTTCACGCCATTCTCCTGCCTCAGCCTCCCGAGTAGCTAGGACTACAGGCGCCCACCACCACGTCCTGCTAATTTTTTGTATTTTTAGTAGAGACGGGGTTTCACCGTGTTAGCCAGGATGGTCTCAATCTCCTGACCTCGTGATCCACCCACCTTGACCTCCCAAAGTGCTGGGATTACAGGCGTGAGCCACTGCGCCCGGCCTCTATAAGCTTTTTTATATTATATATATATATATATATATATATAACTTATTTATTGATTTTTTTACTCGTTAAACTTTTTTGTTAAAAAAGTAAGACACAGACATACACATTAGCTGAGGCCTATACAGGGTCAGGATCATCAATGTCAGAGTCATCAATATCACTGTCTTCCACCTCCACATCTTGTCCCACTTGCAGGCTTTCAAGGGCAATAACAGGCATAGAGCTATCCTCTCCTATGATAATAATGCCTTCTTCTGGAATACCTCTTGAAGGACCTGCCAGAGGCGTAGATTTATTTACAACAGCATCACCAGAAACACATGAGAATGCTTTATGCCATGTCTTTAAAACAGCTACCACAGTATCACTAGGTGATAGGACATTTTCCACTCCATTATAATTTTATGGAGATCATTGTGCGTGGTGCATGGCTGTGTTTGTGTGCACGTCTCACCCTCTCTTAAGAGCACAAAGAGCCTTCCTTTTTTATTCTTTTGTCCCTTATAGCACTTAGCACAGTACCTTGCATTTTACCATCAGTAATAACAAAAACAACAATAAATTTAGCCCAGGGTTCACTGCAAAAAAGAACAAAAGATCAATCTAAAGATGTGATTTTAATTAATACGTAG
Seq C2 exon
GTGTGGGAAATGCTACTGCCTGTGTCTTACATGATGTTATCTACGTCATTGGTGGCCACTGTGGCTACAGAGGAAGCTGCACCTATGACAAAGTTCAGAGCTACAATTCCGATATCAACGAATGGAGCCTCATCACCTCCAGTCCACATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000213160-KLHL23:NM_144711:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.020
Domain overlap (PFAM):
C1:
PF0065126=BTB=WD(100=26.9),PF0770710=BACK=WD(100=25.2),PF0134420=Kelch_1=WD(100=8.1),PF0134420=Kelch_1=WD(100=11.6),PF0134420=Kelch_1=WD(100=11.4)
A:
NA
C2:
PF0134420=Kelch_1=WD(100=90.4)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)