HsaEX0002427 @ hg19
Exon Skipping
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif, 13 [Source:HGNC Symbol;Acc:1366]
Coordinates
chr9:136297709-136302075:+
Coord C1 exon
chr9:136297709-136297813
Coord A exon
chr9:136298498-136298649
Coord C2 exon
chr9:136301949-136302075
Length
152 bp
Sequences
Splice sites
3' ss Seq
AAGCCATCCTTGCCTTGCAGTGG
3' ss Score
5.77
5' ss Seq
CAGGTACCG
5' ss Score
10.05
Exon sequences
Seq C1 exon
GATATGTGCCAGGCCCTCTCCTGCCACACAGACCCGCTGGACCAAAGCAGCTGCAGCCGCCTCCTCGTTCCTCTCCTGGATGGGACAGAATGTGGCGTGGAGAAG
Seq A exon
TGGTGCTCCAAGGGTCGCTGCCGCTCCCTGGTGGAGCTGACCCCCATAGCAGCAGTGCATGGGCGCTGGTCTAGCTGGGGTCCCCGAAGTCCTTGCTCCCGCTCCTGCGGAGGAGGTGTGGTCACCAGGAGGCGGCAGTGCAACAACCCCAG
Seq C2 exon
GCCTGCGAGAAGACCCAGCTGGAGTTCATGTCGCAACAGTGCGCCAGGACCGACGGCCAGCCGCTGCGCTCCTCCCCTGGCGGCGCCTCCTTCTACCACTGGGGTGCTGCTGTACCACACAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323_MULTIEX2-1/12=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.023
Domain overlap (PFAM):
C1:
PF135821=Reprolysin_3=PD(3.3=11.1)
A:
PF0009014=TSP_1=PU(53.8=54.9)
C2:
PF0009014=TSP_1=PD(1.9=2.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATATGTGCCAGGCCCTCTCC
R:
TACAGCAGCACCCCAGTGG
Band lengths:
219-371
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)