HsaEX0002431 @ hg38
Exon Skipping
Gene
ENSG00000160323 | ADAMTS13
Description
ADAM metallopeptidase with thrombospondin type 1 motif 13 [Source:HGNC Symbol;Acc:HGNC:1366]
Coordinates
chr9:133433378-133436955:+
Coord C1 exon
chr9:133433378-133433529
Coord A exon
chr9:133433641-133433704
Coord C2 exon
chr9:133436829-133436955
Length
64 bp
Sequences
Splice sites
3' ss Seq
TGTCTGCTGGGCATTTTCAGACC
3' ss Score
6.71
5' ss Seq
CAGGTAGGC
5' ss Score
9.88
Exon sequences
Seq C1 exon
TGGTGCTCCAAGGGTCGCTGCCGCTCCCTGGTGGAGCTGACCCCCATAGCAGCAGTGCATGGGCGCTGGTCTAGCTGGGGTCCCCGAAGTCCTTGCTCCCGCTCCTGCGGAGGAGGTGTGGTCACCAGGAGGCGGCAGTGCAACAACCCCAG
Seq A exon
ACCTGCCTTTGGGGGGCGTGCATGTGTTGGTGCTGACCTCCAGGCCGAGATGTGCAACACTCAG
Seq C2 exon
GCCTGCGAGAAGACCCAGCTGGAGTTCATGTCGCAACAGTGCGCCAGGACCGACGGCCAGCCGCTGCGCTCCTCCCCTGGCGGCGCCTCCTTCTACCACTGGGGTGCTGCTGTACCACACAGCCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160323_MULTIEX2-5/22=4-6
Average complexity
S
Mappability confidence:
95%=100=95%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.058 A=0.000 C2=0.023
Domain overlap (PFAM):
C1:
PF0009014=TSP_1=PU(53.8=54.9)
A:
PF0009014=TSP_1=FE(40.4=100)
C2:
PF0009014=TSP_1=PD(1.9=2.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGACCCCCATAGCAGCAGT
R:
ACATGAACTCCAGCTGGGTCT
Band lengths:
147-211
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development