HsaEX0003159 @ hg38
Exon Skipping
Gene
ENSG00000188157 | AGRN
Description
agrin [Source:HGNC Symbol;Acc:HGNC:329]
Coordinates
chr1:1045733-1046265:+
Coord C1 exon
chr1:1045733-1045876
Coord A exon
chr1:1045964-1046088
Coord C2 exon
chr1:1046160-1046265
Length
125 bp
Sequences
Splice sites
3' ss Seq
TTCCCATGCCCGTGCCCCAGACG
3' ss Score
6.25
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
CCTGCAGCTGTGATCCCCAAGGCGCCGTGCGGGATGACTGTGAGCAGATGACGGGGCTGTGCTCGTGTAAGCCCGGGGTGGCTGGACCCAAGTGTGGGCAGTGTCCAGACGGCCGTGCCCTGGGCCCCGCGGGCTGTGAAGCTG
Seq A exon
ACGCTTCTGCGCCTGCGACCTGTGCGGAGATGCGCTGTGAGTTCGGTGCGCGGTGCGTGGAGGAGTCTGGCTCAGCCCACTGTGTCTGCCCGATGCTCACCTGTCCAGAGGCCAACGCTACCAAG
Seq C2 exon
GTCTGTGGGTCAGATGGAGTCACATACGGCAACGAGTGTCAGCTGAAGACCATCGCCTGCCGCCAGGGCCTGCAAATCTCTATCCAGAGCCTGGGCCCGTGCCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188157-'37-38,'37-35,38-38
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.028
Domain overlap (PFAM):
C1:
PF0005319=Laminin_EGF=PU(85.5=95.9)
A:
PF0005319=Laminin_EGF=PD(12.7=16.7),PF0764810=Kazal_2=PU(16.7=16.7)
C2:
PF0764810=Kazal_2=PD(78.6=91.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCAGCTGTGATCCCCAAG
R:
TGGATAGAGATTTGCAGGCCC
Band lengths:
229-354
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development