HsaEX0008420 @ hg38
Exon Skipping
Gene
ENSG00000141867 | BRD4
Description
bromodomain containing 4 [Source:HGNC Symbol;Acc:HGNC:13575]
Coordinates
chr19:15267416-15269042:-
Coord C1 exon
chr19:15268905-15269042
Coord A exon
chr19:15268154-15268281
Coord C2 exon
chr19:15267416-15267551
Length
128 bp
Sequences
Splice sites
3' ss Seq
GCCAGATCATTTGTTTACAGTTC
3' ss Score
3.5
5' ss Seq
TAGGTGAGT
5' ss Score
8.83
Exon sequences
Seq C1 exon
GATTACTATAAGATCATTAAAACGCCTATGGATATGGGAACAATAAAGAAGCGCTTGGAAAACAACTATTACTGGAATGCTCAGGAATGTATCCAGGACTTCAACACTATGTTTACAAATTGTTACATCTACAACAAG
Seq A exon
TTCAGACCACAGATGTGATTAAAATCAACCCTTTCAAATAGAACGACTCTGGAGGGAGACACTATACAGAACTCAGCTTTTGACCTCTGCTGGTGTAGTGGGTAAAAATGCCCAGAAGAGATGGGTAG
Seq C2 exon
CCTGGAGATGACATAGTCTTAATGGCAGAAGCTCTGGAAAAGCTCTTCTTGCAAAAAATAAATGAGCTACCCACAGAAGAAACCGAGATCATGATAGTCCAGGCAAAAGGAAGAGGACGTGGGAGGAAAGAAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000141867_MULTIEX3-1/5=C1-2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.357
Domain overlap (PFAM):
C1:
PF0043920=Bromodomain=FE(52.3=100)
A:
PF0043920=Bromodomain=PD(5.0=66.7)
C2:
PF0043920=Bromodomain=PD(11.6=21.7)
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AACGCCTATGGATATGGGAAC
R:
TTTCCTCCCACGTCCTCTTCC
Band lengths:
247-375
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development