HsaEX0014013 @ hg19
Exon Skipping
Gene
ENSG00000158402 | CDC25C
Description
cell division cycle 25 homolog C (S. pombe) [Source:HGNC Symbol;Acc:1727]
Coordinates
chr5:137664173-137666907:-
Coord C1 exon
chr5:137666676-137666907
Coord A exon
chr5:137665242-137665336
Coord C2 exon
chr5:137664173-137664218
Length
95 bp
Sequences
Splice sites
3' ss Seq
GTACTATTATGTCTCAACAGAGG
3' ss Score
7.74
5' ss Seq
CTGGTAGGG
5' ss Score
6.35
Exon sequences
Seq C1 exon
CTAGGTTTTGTTTTTCTCCTGGTGAGAATTCGAAGACCATGTCTACGGAACTCTTCTCATCCACAAGAGAGGAAGGAAGCTCTGGCTCAGGACCCAGTTTTAGGTCTAATCAAAGGAAAATGTTAAACCTGCTCCTGGAGAGAGACACTTCCTTTACCGTCTGTCCAGATGTCCCTAGAACTCCAGTGGGCAAATTTCTTGGTGATTCTGCAAACCTAAGCATTTTGTCTGG
Seq A exon
AGGAACCCCAAAACGTTGCCTCGATCTTTCGAATCTTAGCAGTGGGGAGATAACTGCCACTCAGCTTACCACTTCTGCAGACCTTGATGAAACTG
Seq C2 exon
GTCACCTGGATTCTTCAGGACTTCAGGAAGTGCATTTAGCTGGGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158402_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.387 A=0.515 C2=0.632
Domain overlap (PFAM):
C1:
NO
A:
PF066178=M-inducer_phosp=PU(6.2=12.1)
C2:
PF066178=M-inducer_phosp=FE(23.1=100)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCTGGCTCAGGACCCAGTTTT
R:
AGTCCTGAAGAATCCAGGTGAC
Band lengths:
174-269
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)