HsaEX0014067 @ hg38
Exon Skipping
Gene
ENSG00000143776 | CDC42BPA
Description
CDC42 binding protein kinase alpha [Source:HGNC Symbol;Acc:HGNC:1737]
Coordinates
chr1:227213136-227254155:-
Coord C1 exon
chr1:227254064-227254155
Coord A exon
chr1:227219263-227219420
Coord C2 exon
chr1:227213136-227213219
Length
158 bp
Sequences
Splice sites
3' ss Seq
GTTTTCCTTTTTGCTTTCAGGAA
3' ss Score
11.71
5' ss Seq
CAGGTGTCA
5' ss Score
1.32
Exon sequences
Seq C1 exon
CTAAACCATTTACTTCTAAAGTGAAACAAATGCGATTACATAGAGAAGACTTTGAAATATTAAAGGTGATTGGTCGAGGAGCTTTTGGGGAG
Seq A exon
GAAAACCTTTAACTTACGCCCTGGGTGTTGCCTGTCAACAGTTTCCTGGTGGCTCACCGCTTCTGCCTGCTCCAGCCTTGCTCCGGCAGCTTCAAGGCTTCTGGGCTTCAGAGCTTGTTGTGAAAGCTTGCTGCTTTGGCCTGCTACCCCTGCTTCAG
Seq C2 exon
GTTGCTGTAGTAAAACTAAAAAATGCAGATAAAGTGTTTGCCATGAAAATATTGAATAAATGGGAAATGCTGAAAAGAGCTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000143776_MULTIEX1-3/8=1-4
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PU(4.9=41.9)
A:
NA
C2:
PF0006920=Pkinase=FE(10.1=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTTCTAAAGTGAAACAAATGCGA
R:
TCAGCTCTTTTCAGCATTTCCCA
Band lengths:
164-322
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development