HsaEX0016094 @ hg19
Exon Skipping
Gene
ENSG00000044459 | CNTLN
Description
centlein, centrosomal protein [Source:HGNC Symbol;Acc:23432]
Coordinates
chr9:17236407-17298350:+
Coord C1 exon
chr9:17236407-17236586
Coord A exon
chr9:17273731-17273864
Coord C2 exon
chr9:17298188-17298350
Length
134 bp
Sequences
Splice sites
3' ss Seq
TATAAGCACTCTAATTTTAGACC
3' ss Score
4.88
5' ss Seq
CAGGCAAGT
5' ss Score
3.1
Exon sequences
Seq C1 exon
GACACTAAGGAGTGTGTACAGAACAAAGAAGAGCAAAACAGACTAGTTATAAAAAATCTGGAGGAGGAAAACAAGAAATTAAGTACCCGCTGCACTGACCTGCTAAATGACCTGGAGAAATTGAGGAAGCAGGAAGCACATTTGAGAAAAGAAAAATATAGCACTGATGCAAAAATAAAG
Seq A exon
ACCTTTGAAGACAATTTAATTGAAGCAAGGAAAGAAGTTGAAGTATCACAGAGTAAATACAATGCTCTATCATTACAGTTGAGTAATAAACAGACTGAACTTATCCAGAAGGATATGGATATTACCCTGGTCAG
Seq C2 exon
GAAGGAACTGCAGGAGCTGCAGAATCTTTACAAACAGAACAGTACACATACAGCCCAGCAAGCAGAGCTGATCCAGCAGCTTCAGGTTCTCAATATGGACACACAAAAAGTACTGAGAAATCAGGAAGATGTTCACACAGCTGAAAGTATATCATATCAAAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000044459_MULTIEX1-5/5=4-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.063 A=0.000 C2=0.172
Domain overlap (PFAM):
C1:
PF061568=DUF972=PD(20.3=25.0)
A:
NO
C2:
PF048997=MbeD_MobD=PU(15.7=14.5)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTAAGTACCCGCTGCACTGAC
R:
CAGCTGTGTGAACATCTTCCTGA
Band lengths:
245-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)