HsaEX0018320 @ hg19
Exon Skipping
Gene
ENSG00000187048 | CYP4A11
Description
cytochrome P450, family 4, subfamily A, polypeptide 11 [Source:HGNC Symbol;Acc:2642]
Coordinates
chr1:47399618-47400231:-
Coord C1 exon
chr1:47400125-47400231
Coord A exon
chr1:47399848-47400038
Coord C2 exon
chr1:47399618-47399751
Length
191 bp
Sequences
Splice sites
3' ss Seq
TTTCACCACGGTCTTCCCAGATG
3' ss Score
6.94
5' ss Seq
CTGGTGAGT
5' ss Score
10.1
Exon sequences
Seq C1 exon
ACCAAGTGATCCAACTGAGGAAGGCTCAACTACAGAAGGAGGGGGAGCTGGAGAAGATCAAGAGGAAGAGGCATTTGGATTTTCTGGATATCCTCCTCTTGGCCAAA
Seq A exon
ATGGAGAATGGGAGCATCTTGTCAGACAAGGACCTCCGTGCTGAGGTGGACACGTTCATGTTTGAGGGCCACGACACCACAGCCAGTGGGATCTCCTGGATCCTCTATGCTCTGGCCACACACCCCAAGCATCAGGAGAGGTGCCGGGAGGAGATCCACAGCCTCCTGGGTGATGGAGCCTCCATCACCTG
Seq C2 exon
GAACCACCTGGACCAGATGCCCTACACCACCATGTGCATTAAGGAGGCACTGAGGCTCTACCCACCGGTGCCAGGCATTGGCAGAGAGCTCAGCACTCCCGTCACCTTCCCTGATGGGCGCTCCTTGCCCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000187048_MULTIEX1-1/3=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.221 A=0.097 C2=0.022
Domain overlap (PFAM):
C1:
PF0006717=p450=PD(5.3=16.2)
A:
PF0006717=p450=FE(13.8=100)
C2:
PF0006717=p450=FE(11.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAAGTGATCCAACTGAGGAAGG
R:
GCAAGGAGCGCCCATCAG
Band lengths:
234-425
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)