HsaEX0019990 @ hg38

Exon Skipping

Gene

ENSG00000104936 | DMPK

Description

dystrophia myotonica protein kinase [Source:HGNC Symbol;Acc:HGNC:2933]

Coordinates

chr19:45769736-45771665:-

Coord C1 exon

chr19:45771568-45771665

Coord A exon

chr19:45770971-45771060

Coord C2 exon

chr19:45769736-45770640

Length

90 bp

Sequences

Splice sites

3' ss Seq

CCTGTCCCTTCTCTCTCCAGCTA

3' ss Score

12.23

5' ss Seq

AGGGTACGT

5' ss Score

9.15

Exon sequences

Seq C1 exon

TCAACTACGCGAGGCAGAGGCTCGGAACCGGGACCTAGAGGCACACGTCCGGCAGTTGCAGGAGCGGATGGAGTTGCTGCAGGCAGAGGGAGCCACAG

Seq A exon

CTAGATGGCCCCCCGGCCGTGGCTGTGGGCCAGTGCCCGCTGGTGGGGCCAGGCCCCATGCACCGCCGCCACCTGCTGCTCCCTGCCAGG

Seq C2 exon

GTCCCTAGGCCTGGCCTATCGGAGGCGCTTTCCCTGCTCCTGTTCGCCGTTGTTCTGTCTCGTGCCGCCGCCCTGGGCTGCATTGGGTTGGTGGCCCACGCCGGCCAACTCACCGCAGTCTGGCGCCGCCCAGGAGCCGCCCGCGCTCCCTGAACCCTAGAACTGTCTTCGACTCCGGGGCCCCGTTGGAAGACTGAGTGCCCGGGGCACGGCACAGAAGCCGCGCCCACCGCCTGCCAGTTCACAACCGCTCCGAGCGTGGGTCTCCGCCCAGCTCCAGTCCTGTGATCCGGGCCCGCCCCCTAGCGGCCGGGGAGGGAGGGGCCGGGTCCGCGGCCGGCGAACGGGGCTCGAAGGGTCCTTGTAGCCGGGAATGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGCTGGGGGGATCACAGACCATTTCTTTCTTTCGGCCAGGCTGAGGCCCTGACGTGGATGGGCAAACTG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000104936_MULTIEX1-2/2=C1-C2

Average complexity

C2*

Mappability confidence:

100%=100=100%

Protein Impact

Alternative protein isoforms (Ref)

No structure available

Features

Disorder rate (Iupred):

C1=0.846 A=0.546 C2=0.174

Domain overlap (PFAM):

C1:

PF041569=IncA=FE(31.4=100),PF0157614=Myosin_tail_1=FE(34.7=100),PF0126119=AP_endonuc_2=FE(28.0=100),PF139491=ALIX_LYPXL_bnd=FE(33.3=100),PF032458=Phage_lysis=FE(31.4=100),PF088265=DMPK_coil=PD(47.5=85.3)

A:

NO

C2:

NO

Main Inclusion Isoform:

ENSP00000471832