HsaEX0020111 @ hg38
Exon Skipping
Gene
ENSG00000197653 | DNAH10
Description
dynein axonemal heavy chain 10 [Source:HGNC Symbol;Acc:HGNC:2941]
Coordinates
chr12:123875231-123879357:+
Coord C1 exon
chr12:123875231-123875491
Coord A exon
chr12:123877736-123877908
Coord C2 exon
chr12:123879264-123879357
Length
173 bp
Sequences
Splice sites
3' ss Seq
GGTGTCTTTGCATTTTTCAGACG
3' ss Score
7.13
5' ss Seq
GCGGTGAGT
5' ss Score
10.49
Exon sequences
Seq C1 exon
GTGGATGAATATGGCACGCAGCAGCCCATTGCCTTGCTGAAGCTGCTGTTGGAAAAAGGCTACTTATATGACCGTGGGAAGGAGCTGAACTGTAAAAGCATTCGAGACCTTGGCTTTATTGCTGCAATGGGAAAGGCTGGAGGAGGCCGCAATGAAGTTGACCCAAGATTTATTTCGCTATTCAGTGTCTTCAATGTGCCATTTCCTTCAGAGGAGTCTCTGCATTTAATTTATTCCTCCATCCTGAAAGGCCACACCTCG
Seq A exon
ACGTTTCATGAGAGCATTGTGGCTGTGAGTGGCAAGCTGACATTCTGCACGCTAGCACTTTACAAAAATATTGTGCAAGACCTACCTCCCACTCCGTCAAAGTTCCATTACATCTTCAACCTTCGAGATCTCTCACGGGTTTTTAATGGTCTTGTCCTCACTAACCCGGAGCG
Seq C2 exon
ATTCCAGACGGTGGCCCAGATGGTGAGAGTCTGGAGGAATGAGTGTCTGAGAGTCTTCCACGACCGGCTGATCAGTGAAACAGACAAGCAGCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000197653-'62-61,'62-60,63-61
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127752=AAA_7=FE(31.6=100)
A:
PF127752=AAA_7=FE(21.0=100)
C2:
PF127752=AAA_7=PD(5.1=43.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGCTGCTGTTGGAAAAAGGCT
R:
TCCAGACTCTCACCATCTGGG
Band lengths:
256-429
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development