HsaEX0023633 @ hg38
Exon Skipping
Gene
ENSG00000088926 | F11
Description
coagulation factor XI [Source:HGNC Symbol;Acc:HGNC:3529]
Coordinates
chr4:186275787-186280121:+
Coord C1 exon
chr4:186275787-186275896
Coord A exon
chr4:186276231-186276390
Coord C2 exon
chr4:186280012-186280121
Length
160 bp
Sequences
Splice sites
3' ss Seq
ATAGTTCTTCCGTCGCGCAGCTT
3' ss Score
4.56
5' ss Seq
AAGGTAAGG
5' ss Score
10.51
Exon sequences
Seq C1 exon
TAACATTTGTCTACTGAAGCACACCCAAACAGGGACACCAACCAGAATAACGAAGCTCGATAAAGTGGTGTCTGGATTTTCACTGAAATCCTGTGCACTTTCTAATCTGG
Seq A exon
CTTGTATTAGGGACATTTTCCCTAATACGGTGTTTGCAGACAGCAACATCGACAGTGTCATGGCTCCCGATGCTTTTGTCTGTGGCCGAATCTGCACTCATCATCCCGGTTGCTTGTTTTTTACCTTCTTTTCCCAGGAATGGCCCAAAGAATCTCAAAG
Seq C2 exon
AAATCTTTGTCTCCTTAAAACATCTGAGAGTGGATTGCCCAGTACACGCATTAAAAAGAGCAAAGCTCTTTCTGGTTTCAGTCTACAAAGCTGCAGGCACAGCATCCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000088926_MULTIEX1-3/3=2-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0002421=PAN_1=PD(36.9=81.6)
A:
PF0002421=PAN_1=PU(61.9=96.3)
C2:
PF0002421=PAN_1=PD(36.9=81.6)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACATTTGTCTACTGAAGCACACCC
R:
CTGGGATGCTGTGCCTGC
Band lengths:
218-378
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development