HsaEX0023636 @ hg19
Exon Skipping
Gene
ENSG00000131187 | F12
Description
coagulation factor XII (Hageman factor) [Source:HGNC Symbol;Acc:3530]
Coordinates
chr5:176830482-176831414:-
Coord C1 exon
chr5:176831197-176831414
Coord A exon
chr5:176830860-176831091
Coord C2 exon
chr5:176830482-176830618
Length
232 bp
Sequences
Splice sites
3' ss Seq
CAGCCCCTGCTCCTCCACAGCCT
3' ss Score
6.13
5' ss Seq
CCGGCGAGT
5' ss Score
3.14
Exon sequences
Seq C1 exon
GAACCCGGACAACGACATCCGCCCGTGGTGCTTCGTGCTGAACCGCGACCGGCTGAGCTGGGAGTACTGCGACCTGGCACAGTGCCAGACCCCAACCCAGGCGGCGCCTCCGACCCCGGTGTCCCCTAGGCTTCATGTCCCACTCATGCCCGCGCAGCCGGCACCGCCGAAGCCTCAGCCCACGACCCGGACCCCGCCTCAGTCCCAGACCCCGGGAG
Seq A exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
Seq C2 exon
GCCCGCACCCGAGGATCTGACGGTGGTGCTCGGCCAGGAACGCCGTAACCACAGCTGTGAGCCGTGCCAGACGTTGGCCGTGCGCTCCTACCGCTTGCACGAGGCCTTCTCGCCCGTCAGCTACCAGCACGACCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187_MULTIEX1-3/3=2-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.554 A=0.218 C2=0.064
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PD(35.4=37.8)
A:
PF0008921=Trypsin=PU(18.6=56.4)
C2:
PF0008921=Trypsin=FE(19.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAGCTGGGAGTACTGCGA
R:
CAGGTCGTGCTGGTAGCTGA
Band lengths:
302-534
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)