HsaEX0023636 @ hg38
Exon Skipping
Gene
ENSG00000131187 | F12
Description
coagulation factor XII [Source:HGNC Symbol;Acc:HGNC:3530]
Coordinates
chr5:177403481-177404413:-
Coord C1 exon
chr5:177404196-177404413
Coord A exon
chr5:177403859-177404090
Coord C2 exon
chr5:177403481-177403617
Length
232 bp
Sequences
Splice sites
3' ss Seq
CAGCCCCTGCTCCTCCACAGCCT
3' ss Score
6.13
5' ss Seq
CCGGCGAGT
5' ss Score
3.14
Exon sequences
Seq C1 exon
GAACCCGGACAACGACATCCGCCCGTGGTGCTTCGTGCTGAACCGCGACCGGCTGAGCTGGGAGTACTGCGACCTGGCACAGTGCCAGACCCCAACCCAGGCGGCGCCTCCGACCCCGGTGTCCCCTAGGCTTCATGTCCCACTCATGCCCGCGCAGCCGGCACCGCCGAAGCCTCAGCCCACGACCCGGACCCCGCCTCAGTCCCAGACCCCGGGAG
Seq A exon
CCTTGCCGGCGAAGCGGGAGCAGCCGCCTTCCCTGACCAGGAACGGCCCACTGAGCTGCGGGCAGCGGCTCCGCAAGAGTCTGTCTTCGATGACCCGCGTCGTTGGCGGGCTGGTGGCGCTACGCGGGGCGCACCCCTACATCGCCGCGCTGTACTGGGGCCACAGTTTCTGCGCCGGCAGCCTCATCGCCCCCTGCTGGGTGCTGACGGCCGCTCACTGCCTGCAGGACCG
Seq C2 exon
GCCCGCACCCGAGGATCTGACGGTGGTGCTCGGCCAGGAACGCCGTAACCACAGCTGTGAGCCGTGCCAGACGTTGGCCGTGCGCTCCTACCGCTTGCACGAGGCCTTCTCGCCCGTCAGCTACCAGCACGACCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000131187-'12-17,'12-15,13-17
Average complexity
S
Mappability confidence:
89%=75=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.554 A=0.218 C2=0.064
Domain overlap (PFAM):
C1:
PF0005113=Kringle=PD(35.4=37.8)
A:
PF0008921=Trypsin=PU(18.6=56.4)
C2:
PF0008921=Trypsin=FE(19.4=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGAGCTGGGAGTACTGCGA
R:
CAGGTCGTGCTGGTAGCTGA
Band lengths:
302-534
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development