HsaEX0026035 @ hg19
Exon Skipping
Gene
ENSG00000157827 | FMNL2
Description
formin-like 2 [Source:HGNC Symbol;Acc:18267]
Coordinates
chr2:153476023-153482076:+
Coord C1 exon
chr2:153476023-153476232
Coord A exon
chr2:153477476-153477605
Coord C2 exon
chr2:153481952-153482076
Length
130 bp
Sequences
Splice sites
3' ss Seq
CGTCTACCACTTTCTTCTAGAAC
3' ss Score
8.17
5' ss Seq
GTTGTCAGT
5' ss Score
-1.59
Exon sequences
Seq C1 exon
TGCAAAATGGTCCAGTAACACCACCTATGCCACCGCCGCCGCCGCCCCCTCCTCCACCTCCTCCTCCCCCACCGCCCCCTCCGCCTCCTCCTCTCCCAGGCCCTGCAGCTGAGACTGTACCAGCTCCTCCCTTAGCACCTCCCCTTCCCTCTGCACCTCCGCTGCCTGGAACATCTTCACCCACAGTGGTTTTCAACTCAGGATTAGCAG
Seq A exon
AACTTTTATTACTTCTGAAGGAGAAAAGTTGGAGCAGAGTCATCGTGGAACTGATGGACTATGGAATATAAACAGACAAACAAGAAACCTCATATCAAGCCCCGGGAATGTGTTCCATCACCAGGCTGTT
Seq C2 exon
CTGTGAAAATTAAGAAGCCAATCAAGACGAAGTTCAGAATGCCAGTGTTTAACTGGGTTGCTCTGAAGCCCAATCAGATCAATGGCACAGTCTTCAATGAAATTGATGATGAGCGAATTCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827-'22-28,'22-25,23-28
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.954 A=0.000 C2=0.084
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0218118=FH2=PU(10.4=90.5)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAACACCACCTATGCCACCG
R:
ACACTGGCATTCTGAACTTCGT
Band lengths:
244-374
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)