HsaEX0026035 @ hg38
Exon Skipping
Gene
ENSG00000157827 | FMNL2
Description
formin like 2 [Source:HGNC Symbol;Acc:HGNC:18267]
Coordinates
chr2:152619509-152625562:+
Coord C1 exon
chr2:152619509-152619718
Coord A exon
chr2:152620962-152621091
Coord C2 exon
chr2:152625438-152625562
Length
130 bp
Sequences
Splice sites
3' ss Seq
CGTCTACCACTTTCTTCTAGAAC
3' ss Score
8.17
5' ss Seq
GTTGTCAGT
5' ss Score
-1.59
Exon sequences
Seq C1 exon
TGCAAAATGGTCCAGTAACACCACCTATGCCACCGCCGCCGCCGCCCCCTCCTCCACCTCCTCCTCCCCCACCGCCCCCTCCGCCTCCTCCTCTCCCAGGCCCTGCAGCTGAGACTGTACCAGCTCCTCCCTTAGCACCTCCCCTTCCCTCTGCACCTCCGCTGCCTGGAACATCTTCACCCACAGTGGTTTTCAACTCAGGATTAGCAG
Seq A exon
AACTTTTATTACTTCTGAAGGAGAAAAGTTGGAGCAGAGTCATCGTGGAACTGATGGACTATGGAATATAAACAGACAAACAAGAAACCTCATATCAAGCCCCGGGAATGTGTTCCATCACCAGGCTGTT
Seq C2 exon
CTGTGAAAATTAAGAAGCCAATCAAGACGAAGTTCAGAATGCCAGTGTTTAACTGGGTTGCTCTGAAGCCCAATCAGATCAATGGCACAGTCTTCAATGAAATTGATGATGAGCGAATTCTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000157827_MULTIEX1-1/4=C1-3
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.952 A=0.000 C2=0.093
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0218118=FH2=PU(10.4=90.5)
Main Inclusion Isoform:
ENST00000288670fB2771
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTAACACCACCTATGCCACCG
R:
ACACTGGCATTCTGAACTTCGT
Band lengths:
244-374
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development