HsaEX0026310 @ hg19
Exon Skipping
Gene
ENSG00000136877 | FPGS
Description
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:3824]
Coordinates
chr9:130570837-130572113:+
Coord C1 exon
chr9:130570837-130570984
Coord A exon
chr9:130571079-130571168
Coord C2 exon
chr9:130571963-130572113
Length
90 bp
Sequences
Splice sites
3' ss Seq
TGGTCTCACACACCCCGCAGGTG
3' ss Score
9.34
5' ss Seq
TCGGTGAGT
5' ss Score
11.11
Exon sequences
Seq C1 exon
TGTCCTCTATACCTGTGTCCGATGCTGGAGGCCCTCGAGGAAGGGGGGCCGCCGCTGACCCTGGGCCTGGAGGGGGAGCACCAGCGGTCCAACGCCGCCTTGGCCTTGCAGCTGGCCCACTGCTGGCTGCAGCGGCAGGACCGCCATG
Seq A exon
GTGCTGGGGAGCCAAAGGCATCCAGGCCAGGGCTCCTGTGGCAGCTGCCCCTGGCACCTGTGTTCCAGCCCACATCCCACATGCGGCTCG
Seq C2 exon
GGCTTCGGAACACGGAGTGGCCGGGCCGGACGCAGGTGCTGCGGCGCGGGCCCCTCACCTGGTACCTGGACGGTGCGCACACCGCCAGCAGCGCGCAGGCCTGCGTGCGCTGGTTCCGCCAGGCGCTGCAGGGCCGCGAGAGGCCGAGCGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136877-'22-28,'22-27,24-28
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.140 A=0.109 C2=0.107
Domain overlap (PFAM):
C1:
PF082457=Mur_ligase_M=PD(17.8=76.0)
A:
PF082457=Mur_ligase_M=PD(2.2=13.3)
C2:
PF0287516=Mur_ligase_C=PU(54.3=86.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTCCTCTATACCTGTGTCCGA
R:
CACTCCGTGTTCCGAAGCC
Band lengths:
167-257
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)