HsaEX0026313 @ hg19
Exon Skipping
Gene
ENSG00000136877 | FPGS
Description
folylpolyglutamate synthase [Source:HGNC Symbol;Acc:3824]
Coordinates
chr9:130570513-130571168:+
Coord C1 exon
chr9:130570513-130570590
Coord A exon
chr9:130570837-130570984
Coord C2 exon
chr9:130571079-130571168
Length
148 bp
Sequences
Splice sites
3' ss Seq
CTCCTGCCTGTCTCCCCTAGTGT
3' ss Score
9.9
5' ss Seq
ATGGTGAGT
5' ss Score
10.13
Exon sequences
Seq C1 exon
CAAGGTGTCCCTGCCTTCACTGTGCTCCAACCTGAAGGTCCCCTGGCAGTGCTGAGGGACCGAGCCCAGCAGATCTCA
Seq A exon
TGTCCTCTATACCTGTGTCCGATGCTGGAGGCCCTCGAGGAAGGGGGGCCGCCGCTGACCCTGGGCCTGGAGGGGGAGCACCAGCGGTCCAACGCCGCCTTGGCCTTGCAGCTGGCCCACTGCTGGCTGCAGCGGCAGGACCGCCATG
Seq C2 exon
GTGCTGGGGAGCCAAAGGCATCCAGGCCAGGGCTCCTGTGGCAGCTGCCCCTGGCACCTGTGTTCCAGCCCACATCCCACATGCGGCTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136877_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.140 C2=0.109
Domain overlap (PFAM):
C1:
PF082457=Mur_ligase_M=FE(14.0=100)
A:
PF082457=Mur_ligase_M=PD(17.8=76.0)
C2:
PF082457=Mur_ligase_M=PD(2.2=13.3)
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAAGGTGTCCCTGCCTTCAC
R:
GCATGTGGGATGTGGGCTG
Band lengths:
162-310
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)