HsaEX0032447 @ hg38
Exon Skipping
Gene
ENSG00000259207 | ITGB3
Description
integrin subunit beta 3 [Source:HGNC Symbol;Acc:HGNC:6156]
Coordinates
chr17:47253846-47283549:+
Coord C1 exon
chr17:47253846-47253940
Coord A exon
chr17:47274419-47274504
Coord C2 exon
chr17:47283354-47283549
Length
86 bp
Sequences
Splice sites
3' ss Seq
CCTTTGTCTGTCTGTTGCAGGGC
3' ss Score
12.26
5' ss Seq
GAGGTAAGG
5' ss Score
10.28
Exon sequences
Seq C1 exon
GCGGGAGGCGGACGAGATGCGAGCGCGGCCGCGGCCCCGGCCGCTCTGGGCGACTGTGCTGGCGCTGGGGGCGCTGGCGGGCGTTGGCGTAGGAG
Seq A exon
GGCCCAACATCTGTACCACGCGAGGTGTGAGCTCCTGCCAGCAGTGCCTGGCTGTGAGCCCCATGTGTGCCTGGTGCTCTGATGAG
Seq C2 exon
GCCCTGCCTCTGGGCTCACCTCGCTGTGACCTGAAGGAGAATCTGCTGAAGGATAACTGTGCCCCAGAATCCATCGAGTTCCCAGTGAGTGAGGCCCGAGTACTAGAGGACAGGCCCCTCAGCGACAAGGGCTCTGGAGACAGCTCCCAGGTCACTCAAGTCAGTCCCCAGAGGATTGCACTCCGGCTCCGGCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000259207-'0-1,'0-0,1-1=AN
Average complexity
A_NA
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.111 A=0.000 C2=0.242
Domain overlap (PFAM):
C1:
NO
A:
PF0036213=Integrin_beta=PU(4.0=58.6)
C2:
PF0036213=Integrin_beta=FE(15.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTGGGCGACTGTGCTG
R:
GCCTGTCCTCTAGTACTCGGG
Band lengths:
167-253
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development