HsaEX0032487 @ hg38
Exon Skipping
Gene
ENSG00000105855 | ITGB8
Description
integrin subunit beta 8 [Source:HGNC Symbol;Acc:HGNC:6163]
Coordinates
chr7:20331123-20363722:+
Coord C1 exon
chr7:20331123-20331933
Coord A exon
chr7:20340273-20340468
Coord C2 exon
chr7:20363637-20363722
Length
196 bp
Sequences
Splice sites
3' ss Seq
GTATCGTTTGTTTATTCTAGAGG
3' ss Score
7.18
5' ss Seq
TAGGTATGT
5' ss Score
7.76
Exon sequences
Seq C1 exon
TATGCAGCAGAAGCCCCACCGGCTGGAGAGAAACAAAAGCTCTTTTCTTTGTCCCGGAGCAGGCTGCGGAGCCCTTGCAGAGCCCTCTCTCCAGTCGCCGCCGGGGCCCTTGGCCGTCGAAGGAGGTGCTTCTCGCGGAGACCGCGGGACCCGCCGTGCCGAGCCGGGAGGGCCGCAGGGGCCCTGAGATGCCGAGCGGTGCCCGGGCCCGCTTACCTGCACCGCTTGCTCCGAGCCGCGGGGTCCGCCTGCTAGGCCTGCGGAAAACGTCCTAGCGACACTCGGCCCGCGGGCCCCGAGGTGCGCCCGGGAGGCGCGAGCCCGCGTCCGGAAGGCAGTCAGGCGGCGGGCGCGGGGCGGGCTGTTTTGCATTATGTGCGGCTCGGCCCTGGCTTTTTTTACCGCTGCATTTGTCTGCCTGCAAAACGACCGGCGAGGTCCCGCCTCGTTCCTCTGGGCAGCCTGGGTGTTTTCACTTGTTCTTGGACTGGGCCAAGGTG
Seq A exon
AGGATTGCCAAAAAATTCACAGTCTCGTGATAGTACAGGGTAAGAAAGCAGAGTAGCTGTCAAGGGCTAGTTCAAGTCAAAGCCTATGGAAGAGACCGAGTTTGGAAGTGGAGAGAAGGGCTGGTGATGAAGACAGGAGGATGAAAAACTAGAAATATTCCAGCTCTGAAGAACTGTACCAAATATGTCATATTAG
Seq C2 exon
AAGACAATAGATGTGCATCTTCAAATGCAGCATCCTGTGCCAGGTGCCTTGCGCTGGGTCCAGAATGTGGATGGTGTGTTCAAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105855_MULTIEX1-3/6=1-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
PF0036213=Integrin_beta=PU(4.1=58.6)
Main Inclusion Isoform:
ENST00000222573fB3463
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCTAGCGACACTCGGCC
R:
TTTGAAGATGCACATCTATTGTCTT
Band lengths:
256-452
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development