HsaEX0036161 @ hg19
Exon Skipping
Gene
ENSG00000115318 | LOXL3
Description
lysyl oxidase-like 3 [Source:HGNC Symbol;Acc:13869]
Coordinates
chr2:74763418-74777475:-
Coord C1 exon
chr2:74777312-74777475
Coord A exon
chr2:74776496-74776710
Coord C2 exon
chr2:74763418-74763598
Length
215 bp
Sequences
Splice sites
3' ss Seq
GCTTGTGGCCCCGCCCCCAGGTA
3' ss Score
8.16
5' ss Seq
CAGGTGAGG
5' ss Score
10.07
Exon sequences
Seq C1 exon
GCCGCATCTGGCTGGACAACTTGAGCTGCAGTGGGACCGAGCAGAGTGTGACTGAATGTGCCTCCCGGGGCTGGGGGAACAGTGACTGTACGCACGATGAGGATGCTGGGGTCATCTGCAAAGACCAGCGCCTCCCTGGCTTCTCGGACTCCAATGTCATTGAG
Seq A exon
GTAGAGCATCACCTGCAAGTGGAGGAGGTGCGAATTCGACCCGCCGTTGGGTGGGGCAGACGACCCCTGCCCGTGACGGAGGGGCTGGTGGAAGTCAGGCTTCCTGACGGCTGGTCGCAAGTGTGCGACAAAGGCTGGAGCGCCCACAACAGCCACGTGGTCTGCGGGATGCTGGGCTTCCCCAGCGAAAAGAGGGTCAACGCGGCCTTCTACAG
Seq C2 exon
GCCCGTGTCCGTCTAAAGGGCGGCGCCCACCCTGGAGAGGGCCGGGTAGAAGTCCTGAAGGCCAGCACATGGGGCACAGTCTGTGACCGCAAGTGGGACCTGCATGCAGCCAGCGTGGTGTGTCGGGAGCTGGGCTTCGGGAGTGCTCGAGAAGCTCTGAGTGGCGCTCGCATGGGGCAGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115318_MULTIEX1-1/2=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.012 A=0.025 C2=0.124
Domain overlap (PFAM):
C1:
PF0053013=SRCR=PD(41.7=72.7)
A:
PF0053013=SRCR=PU(48.5=68.1)
C2:
PF0053013=SRCR=PU(67.9=90.2),PF0118612=Lysyl_oxidase=PU(23.9=44.3)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGACAACTTGAGCTGCAGTG
R:
CTTCTCGAGCACTCCCGAAG
Band lengths:
306-521
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)