HsaEX0039547 @ hg19
Exon Skipping
Gene
ENSG00000078403 | MLLT10
Description
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 [Source:HGNC Symbol;Acc:16063]
Coordinates
chr10:21940602-21970305:+
Coord C1 exon
chr10:21940602-21940697
Coord A exon
chr10:21959378-21959633
Coord C2 exon
chr10:21970261-21970305
Length
256 bp
Sequences
Splice sites
3' ss Seq
TTTTTGAATCAAAATGTTAGACT
3' ss Score
0.74
5' ss Seq
AAGGTATTA
5' ss Score
7.04
Exon sequences
Seq C1 exon
AAATATAAAGAGAAGGACAAACACAAACAGAAACACAAGAAGCAGCCAGAACCATCACCTGCATTGGTTCCATCCTTGACTGTTACTACAGAAAAA
Seq A exon
ACTTATACAAGCACTAGCAACAACTCTATATCTGGATCATTGAAGCGCTTGGAAGATACTACTGCACGATTTACAAATGCAAATTTCCAGGAAGTCTCTGCACACACCTCTAGTGGAAAAGATGTTTCAGAGACTAGAGGGTCAGAGGGCAAAGGGAAGAAATCTTCAGCTCACAGCTCAGGTCAAAGGGGAAGAAAGCCTGGTGGTGGAAGAAATCCAGGAACAACTGTGTCAGCAGCTAGCCCTTTTCCTCAAG
Seq C2 exon
AAATTTCCATGCAGTATCGGCATGATGGAGCTTGCCCAACAACTA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000078403_MULTIEX3-3/8=C1-5
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.994 A=1.000 C2=0.723
Domain overlap (PFAM):
C1:
PF105004=SR-25=PD(24.0=56.2)
A:
NO
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGAGAAGGACAAACACAAACAGA
R:
AGTTGTTGGGCAAGCTCCATC
Band lengths:
132-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)