HsaEX0043413 @ hg19
Exon Skipping
Gene
ENSG00000204301 | NOTCH4
Description
notch 4 [Source:HGNC Symbol;Acc:7884]
Coordinates
chr6:32183003-32185043:-
Coord C1 exon
chr6:32184930-32185043
Coord A exon
chr6:32184722-32184844
Coord C2 exon
chr6:32183003-32183162
Length
123 bp
Sequences
Splice sites
3' ss Seq
ACCTTCCTGCTGTGCCACAGGCT
3' ss Score
8.61
5' ss Seq
CAGGTTCAC
5' ss Score
1.23
Exon sequences
Seq C1 exon
GATTCTCCGGCACCCGATGTGAGGAGGATATCGATGAGTGCAGAAGCTCTCCCTGTGCCAATGGTGGGCAGTGCCAGGACCAGCCTGGAGCCTTCCACTGCAAGTGTCTCCCAG
Seq A exon
GCTTTGAAGGGCCACGCTGTCAAACAGAGGTGGATGAGTGCCTGAGTGACCCATGTCCCGTTGGAGCCAGCTGCCTTGATCTTCCAGGAGCCTTCTTTTGCCTCTGCCCCTCTGGTTTCACAG
Seq C2 exon
GCCAGCTCTGTGAGGTTCCCCTGTGTGCTCCCAACCTGTGCCAGCCCAAGCAGATATGTAAGGACCAGAAAGACAAGGCCAACTGCCTCTGTCCTGATGGAAGCCCTGGCTGTGCCCCACCTGAGGACAACTGCACCTGCCACCACGGGCACTGCCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204301_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0000822=EGF=PD(16.1=12.8),PF0764510=EGF_CA=PU(72.5=74.4)
A:
PF0764510=EGF_CA=PD(25.0=23.8),PF0000822=EGF=PU(90.3=66.7)
C2:
PF0000822=EGF=PD(6.5=3.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCGATGTGAGGAGGATATCGA
R:
GCAGGTGCAGTTGTCCTCAG
Band lengths:
242-365
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)