HsaEX0045418 @ hg38
Exon Skipping
Gene
ENSG00000100767 | PAPLN
Description
papilin, proteoglycan like sulfated glycoprotein [Source:HGNC Symbol;Acc:HGNC:19262]
Coordinates
chr14:73265370-73268723:+
Coord C1 exon
chr14:73265370-73265507
Coord A exon
chr14:73266501-73266628
Coord C2 exon
chr14:73268557-73268723
Length
128 bp
Sequences
Splice sites
3' ss Seq
TGGCTGTACTTGGTCCCCAGACA
3' ss Score
7.1
5' ss Seq
TGGGTAAAG
5' ss Score
4.2
Exon sequences
Seq C1 exon
GCTGCGTTTGGACCAGAACCAGCCCCGGGTGGTGGATGCCAGTCCAGGCCAGCGGATCCGGATGACCTGCCGTGCCGAAGGCTTCCCGCCCCCAGCCATCGAGTGGCAGAGAGATGGGCAGCCTGTCTCTTCTCCCAG
Seq A exon
ACACCAGCTGCAGCCTGATGGCTCCCTGGTCATTAGCCGAGTGGCTGTAGAAGATGGCGGCTTCTACACCTGTGTCGCTTTCAATGGGCAGGACCGAGACCAGCGATGGGTCCAGCTCAGAGTTCTGG
Seq C2 exon
GAACGGGCTACCTGTGCAGGCTGATGGCCACCGTGTCCACCAGTCCCCAGATGGCACGCTGCTCATTTACAACTTGCGGGCCAGGGATGAGGGCTCCTACACGTGCAGTGCCTACCAGGGGAGCCAGGCAGTCAGCCGCAGCACCGAGGTGAAGGTGGTCTCACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100767_MULTIEX1-1/2=C1-C2
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.890 A=0.227 C2=0.228
Domain overlap (PFAM):
C1:
PF0767911=I-set=PU(50.0=89.4)
A:
PF0767911=I-set=PD(48.8=93.2)
C2:
PF0767911=I-set=PD(59.8=91.2)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGCGTTTGGACCAGAACCAG
R:
TAGGCACTGCACGTGTAGGAG
Band lengths:
251-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development