HsaEX0046164 @ hg19
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:8772]
Coordinates
chr6:165829677-165832265:-
Coord C1 exon
chr6:165832123-165832265
Coord A exon
chr6:165831841-165831995
Coord C2 exon
chr6:165829677-165829769
Length
155 bp
Sequences
Splice sites
3' ss Seq
TGTGATATCATTCCCACCAGGAC
3' ss Score
8.74
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
Exon sequences
Seq C1 exon
ATATATGCAAAAAACCTGGTGAATGCCGATCGTTGTGCGCTTTTCCAGGTGGACCATAAGAACAAGGAGTTATATTCAGACCTTTTTGATATTGGAGAGGAAAAGGAAGGAAAACCTGTCTTCAAGAAGACCAAAGAGATAAG
Seq A exon
GACCCGCCTCCTGAAGGTAGTACTTCTGGGAATGACATTGCAGGCAGTGCCCGAGAAACCGCGCCTAGGAAGCCTTAGCGTCACTCCTGGAAATGCCGTCTTCCGGAGGCGGTCCTTTTGGAAATCATGTTGGAAAAACTTTCTAGTGCTCCCAG
Seq C2 exon
ATTTTCAATTGAGAAAGGAATTGCTGGCCAAGTAGCAAGAACAGGGGAAGTCCTGAACATTCCAGATGCCTATGCAGACCCACGCTTTAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541-'15-18,'15-17,16-18
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(32.0=100)
A:
PF0159021=GAF=PD(42.6=81.1)
C2:
PF0159021=GAF=FE(21.1=100)
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAACCTGGTGAATGCCGATCG
R:
CTGTTAAAGCGTGGGTCTGCA
Band lengths:
226-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)