HsaEX0046164 @ hg38
Exon Skipping
Gene
ENSG00000112541 | PDE10A
Description
phosphodiesterase 10A [Source:HGNC Symbol;Acc:HGNC:8772]
Coordinates
chr6:165416189-165418777:-
Coord C1 exon
chr6:165418635-165418777
Coord A exon
chr6:165418353-165418507
Coord C2 exon
chr6:165416189-165416281
Length
155 bp
Sequences
Splice sites
3' ss Seq
TGTGATATCATTCCCACCAGGAC
3' ss Score
8.74
5' ss Seq
CAGGTAGGT
5' ss Score
10.28
Exon sequences
Seq C1 exon
ATATATGCAAAAAACCTGGTGAATGCCGATCGTTGTGCGCTTTTCCAGGTGGACCATAAGAACAAGGAGTTATATTCAGACCTTTTTGATATTGGAGAGGAAAAGGAAGGAAAACCTGTCTTCAAGAAGACCAAAGAGATAAG
Seq A exon
GACCCGCCTCCTGAAGGTAGTACTTCTGGGAATGACATTGCAGGCAGTGCCCGAGAAACCGCGCCTAGGAAGCCTTAGCGTCACTCCTGGAAATGCCGTCTTCCGGAGGCGGTCCTTTTGGAAATCATGTTGGAAAAACTTTCTAGTGCTCCCAG
Seq C2 exon
ATTTTCAATTGAGAAAGGAATTGCTGGCCAAGTAGCAAGAACAGGGGAAGTCCTGAACATTCCAGATGCCTATGCAGACCCACGCTTTAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000112541_MULTIEX1-2/4=1-3
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0159021=GAF=FE(32.0=100)
A:
NO
C2:
PF0159021=GAF=FE(21.1=100)
Main Inclusion Isoform:
ENST00000366882fB5049
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAACCTGGTGAATGCCGATCG
R:
CTGTTAAAGCGTGGGTCTGCA
Band lengths:
226-381
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development