HsaEX0046188 @ hg19
Exon Skipping
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A, cGMP-stimulated [Source:HGNC Symbol;Acc:8777]
Coordinates
chr11:72342122-72385497:-
Coord C1 exon
chr11:72385181-72385497
Coord A exon
chr11:72353298-72353370
Coord C2 exon
chr11:72342122-72342183
Length
73 bp
Sequences
Splice sites
3' ss Seq
GCTGTTGTCCAATTCCTCAGGCG
3' ss Score
6.2
5' ss Seq
CAGGTAGGG
5' ss Score
9.46
Exon sequences
Seq C1 exon
TGCATTATCAGACCTGCTCCAACCTCCTCCCAGAGCCAGCCGAGCAGCAGAGGCAGTGGCAGCGGGAGAGGCGGGAGCAGCGGGGCAGCAGAGCTGGATTGGGGTGTTGAGTCCAGGCTGAGTAGGGGGCAGCCCACTGCTCTTGGTCCCTGTGCCTGCTGGGGGTGCCCTGCCCTGAACTCCAGGCAGCGGGGACAGGGCGAGGTGCCACCTTAGTCTGGCTGGGGAGGCGGACGATGAGGAGTGATGGGGCAGGCATGCGGCCACTCCATCCTCTGCAGGAGCCAGCAGTACCCGGCAGCGCGACCGGCTGAGCC
Seq A exon
GCGGGGCCAGCAGGTCTTCCTCAAGCCGGACGAGCCGCCGCCGCCGCCGCAGCCATGCGCCGACAGCCTGCAG
Seq C2 exon
CCAGCCTGGACCCCCTTGCAAAGGAGCCAGGACCCCCAGGGAGTAGAGACGACCGACTGGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642-'0-10,'0-9,7-10
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.250 A=0.821 C2=1.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTTAGTCTGGCTGGGGAG
R:
CAGTCGGTCGTCTCTACTCCC
Band lengths:
168-241
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)