HsaEX0046193 @ hg19
Exon Skipping
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A, cGMP-stimulated [Source:HGNC Symbol;Acc:8777]
Coordinates
chr11:72319706-72353370:-
Coord C1 exon
chr11:72353298-72353370
Coord A exon
chr11:72342122-72342183
Coord C2 exon
chr11:72319706-72319795
Length
62 bp
Sequences
Splice sites
3' ss Seq
TGACCTTCTTGTCTCTGCAGCCA
3' ss Score
10.88
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
GCGGGGCCAGCAGGTCTTCCTCAAGCCGGACGAGCCGCCGCCGCCGCCGCAGCCATGCGCCGACAGCCTGCAG
Seq A exon
CCAGCCTGGACCCCCTTGCAAAGGAGCCAGGACCCCCAGGGAGTAGAGACGACCGACTGGAG
Seq C2 exon
GACGCCTTGCTGAGTCTGGGCTCTGTCATCGACATTTCAGGCCTGCAACGTGCTGTCAAGGAGGCCCTGTCAGCTGTGCTCCCCCGAGTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642_CASSETTE3
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.821 A=1.000 C2=0.006
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCAGGTCTTCCTCAAGCC
R:
CTGACAGGGCCTCCTTGACAG
Band lengths:
139-201
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)