HsaEX0046195 @ hg19
Exon Skipping
Gene
ENSG00000186642 | PDE2A
Description
phosphodiesterase 2A, cGMP-stimulated [Source:HGNC Symbol;Acc:8777]
Coordinates
chr11:72302341-72316270:-
Coord C1 exon
chr11:72316182-72316270
Coord A exon
chr11:72307637-72307692
Coord C2 exon
chr11:72302341-72302400
Length
56 bp
Sequences
Splice sites
3' ss Seq
CATTGCCCTCTCCCCCTCAGTGC
3' ss Score
9.75
5' ss Seq
TTGGTAAGA
5' ss Score
8.85
Exon sequences
Seq C1 exon
GAAACTGTCTACACCTACCTACTGGATGGTGAGTCCCAGCTGGTGTGTGAGGACCCCCCACATGAGCTGCCCCAGGAGGGGAAAGTCCG
Seq A exon
TGCTGGTCATGCCGCTAGCGGACAAGGAGGCTGGGGCCGTGGCAGCTGTCATCTTG
Seq C2 exon
GTGCACTGTGGCCAGCTGAGTGATAATGAGGAATGGAGCCTGCAGGCGGTGGAGAAGCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000186642_MULTIEX1-2/9=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.344 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTACTGGATGGTGAGTCCC
R:
ATGCTTCTCCACCGCCTGC
Band lengths:
133-189
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)