HsaEX0046262 @ hg38
Exon Skipping
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]
Coordinates
chr4:119519045-119521060:-
Coord C1 exon
chr4:119520935-119521060
Coord A exon
chr4:119520307-119520342
Coord C2 exon
chr4:119519045-119519139
Length
36 bp
Sequences
Splice sites
3' ss Seq
ATCCATATCTCTGTCCTTAGATT
3' ss Score
9.23
5' ss Seq
TAGGTAAGT
5' ss Score
9.66
Exon sequences
Seq C1 exon
GTTCTTTGCAGATGGATTTTAAGTGTTAAGAAGAATTATCGGAAGAATGTTGCCTATCATAATTGGAGACATGCCTTTAATACAGCTCAGTGCATGTTTGCTGCTCTAAAAGCAGGCAAAATTCAG
Seq A exon
ATTCTAACTTCAGTGGGAATCGACTAGTTATTCTAG
Seq C2 exon
AACAAGCTGACTGACCTGGAGATACTTGCATTGCTGATTGCTGCACTAAGCCACGATTTGGATCACCGTGGTGTGAATAACTCTTACATACAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735_CASSETTE2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence inclusion
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(9.6=54.8)
A:
NO
C2:
PF0023314=PDEase_I=FE(13.0=100)
Main Inclusion Isoform:
ENST00000264805fB5062
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCCTTTAATACAGCTCAGTGCA
R:
ACCACGGTGATCCAAATCGTG
Band lengths:
127-163
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development