HsaINT0122125 @ hg38
Intron Retention
Gene
ENSG00000138735 | PDE5A
Description
phosphodiesterase 5A [Source:HGNC Symbol;Acc:HGNC:8784]
Coordinates
chr4:119519045-119521060:-
Coord C1 exon
chr4:119520935-119521060
Coord A exon
chr4:119519140-119520934
Coord C2 exon
chr4:119519045-119519139
Length
1795 bp
Sequences
Splice sites
5' ss Seq
CAGGTACTT
5' ss Score
8.17
3' ss Seq
CAATGTCTTTGGTCATGCAGAAC
3' ss Score
5.73
Exon sequences
Seq C1 exon
GTTCTTTGCAGATGGATTTTAAGTGTTAAGAAGAATTATCGGAAGAATGTTGCCTATCATAATTGGAGACATGCCTTTAATACAGCTCAGTGCATGTTTGCTGCTCTAAAAGCAGGCAAAATTCAG
Seq A exon
GTACTTTTTAGAGCCATTCATATATCTAATACATTTTGTTGCTTAGTAGTAAAATTTATAGCATATTCTTTCAATTTCACTTTAAGGTGCACAATGATTTAAAATAATATTTGCTGCCACTTACATAATAAGTTATATTTCGTTAATTAAAGAGGACTAATCTGGCAAAACTACTTCGTTGCTAATTTTCTTCCATATATGATATATATGGCATATTAGAAAACCTTCAAAATAACTTCATGTTGCACGTAAATAGTCTTTGGGCAAATAAATATTTCCTTCTGAGGAAAACACTGCCTTATTAAGAAAAAGTAAGAAAAAGTATCACATTTCTCTTGTTCACATTCAACCTGCTCCATAGTAGAATTCCTCAAAAACCACCTAGTTCCTGAACTTGCTTCATTGATAAGTTAGGGGTCTGTATCGCATTTTCTCTGGAGCACTCAGTAAATTTTGTAAGTACTGTTTCATAGAAAGGGTTTTGGTTTCATATACATTGACCAGAGACTGTTTAAAAGGAAGATCAATGCAGAAAACGTTCAAGTAATTCGTTCCTTTCCAGGCCAAATTTTATCCATATCTCTGTCCTTAGATTCTAACTTCAGTGGGAATCGACTAGTTATTCTAGGTAAGTGATTCCAGGCATCCATCATATAACTGTTTTTAATTCAGAGCTTCCCTGCCTTTTTCTTTTTGTAAATAAATTCTTAAAATGTTATTCTCTGTCTCTACTTTCATAGGGTGCACATTTTAACTGGCTAAATCTAAAAGAAGTGATTGTTATTAAAGAAGTGAGGTGCAATTAAATACAATAGTAGTATTTTCCTACCTTAGCAAACACGTGTAGGTTGAGTATCCCTTATCCGAAATGGGACAAGAAGTGTTTTGGACTTCAGATTTTTTTCAGACTTTGGAATATTTGCATTATACTTACTGGTTGAATATACCTAATCTGAAGATCCAAAATATTCCAATGAGTATTTCCTTTGAGACTTATTGGTGCTCCAAGAGCTTCAGATTTGGAAGCATTTTGGATTTCAGATTAGGGATACTCAACCAGTGTAAGAAATCATGTAAACTTATTTTGGGGTAGGGAAGGTCACAAGGATTATCAACACTGAAAACTGTCCTAGTTCTCTGTGAGGAATAACAAAATGATGATTTTTGTGTTTGTTGTAAAACCTATTTAGAGTACTGAGAGTTCTAGGAAAATACAGCTGATGATAATTTTAACTTGTGTTTTTTGCGAATGAAGGGGAACAGTATTAATGATAATACTCATAGCAGATACTAAAAAATAACCTATATTTAGCTTGAGAGTATATTATGTAACTTTTTAAAGCCAAGTTTTCATTTCAAATCATTTTCTTTCTATTGTTTTGCTTGAATTAACATTGTCTGCATTCCTTAAGGACACAGCAACTGATAGCAGAGAGTGAACAGAATCTGCAGGGAATTAAAAGAGGAAAAAAACAATTATTTAAAGTTTATTATGATTATTTCACATAATAATTAAGAATTAGCAATACTTACTATAGGTGGACAGATTATTAATTTATTGAGGCATTTCAGCTTTTCCTGTTGATAAGTGACATTTGTGGTGATCCCATTCTGAATGACAAAGGACAACTAATTCCCTGAAGAATAGGATTCTAGGGTTAGTCCTTTGTGACTATAGAGAAGTATGTATGTAAAGCACTGAGGGGAAAAAAAAGATTACTGAAAAGAGGTAATATAATGTCCTTCACCACATTATATTTGTTCTCTCTTTCCTCCAATGTCTTTGGTCATGCAG
Seq C2 exon
AACAAGCTGACTGACCTGGAGATACTTGCATTGCTGATTGCTGCACTAAGCCACGATTTGGATCACCGTGGTGTGAATAACTCTTACATACAGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000138735:ENST00000354960:13
Average complexity
IR
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=NA C2=0.000
Domain overlap (PFAM):
C1:
PF0023314=PDEase_I=PU(9.6=54.8)
A:
NA
C2:
PF0023314=PDEase_I=FE(13.0=100)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GTTCTTTGCAGATGGATTTTAAGTGT
R:
TGTAAGAGTTATTCACACCACGGT
Band lengths:
214-2009
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development