HsaEX0052282 @ hg38
Exon Skipping
Gene
ENSG00000136237 | RAPGEF5
Description
Rap guanine nucleotide exchange factor 5 [Source:HGNC Symbol;Acc:HGNC:16862]
Coordinates
chr7:22125604-22136125:-
Coord C1 exon
chr7:22136038-22136125
Coord A exon
chr7:22131037-22131101
Coord C2 exon
chr7:22125604-22125658
Length
65 bp
Sequences
Splice sites
3' ss Seq
TTTTTGTTTTTAATTTTCAGATG
3' ss Score
11.57
5' ss Seq
CTGGTACGT
5' ss Score
9.57
Exon sequences
Seq C1 exon
GATCCTTCCCTAAATCACAAAGCCTACAGAGATGCATTCAAAAAGATGAAGCCACCAAAAATCCCTTTCATGCCCTTATTGCTTAAAG
Seq A exon
ATGTAACATTTATTCATGAAGGAAATAAAACTTTTTTGGATAATCTTGTCAATTTTGAAAAGCTG
Seq C2 exon
CATATGATCGCAGACACTGTCCGAACCCTGAGACACTGCAGGACTAACCAGTTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000136237_MULTIEX1-3/3=2-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.042
Domain overlap (PFAM):
C1:
PF0061714=RasGEF=FE(15.7=100)
A:
PF0061714=RasGEF=FE(11.4=100)
C2:
PF0061714=RasGEF=PD(0.5=5.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATCCTTCCCTAAATCACAAAGCCT
R:
CAAACTGGTTAGTCCTGCAGTGT
Band lengths:
143-208
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development