HsaEX0052402 @ hg38
Exon Skipping
Gene
ENSG00000105122 | RASAL3
Description
RAS protein activator like 3 [Source:HGNC Symbol;Acc:HGNC:26129]
Coordinates
chr19:15451624-15452815:-
Coord C1 exon
chr19:15452658-15452815
Coord A exon
chr19:15452045-15452108
Coord C2 exon
chr19:15451624-15451938
Length
64 bp
Sequences
Splice sites
3' ss Seq
CAATCCCCCGACCCCCACAGGAG
3' ss Score
5.64
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
Exon sequences
Seq C1 exon
TTGGCAGAGCTGCAGTGCGAGGTGGCCGCTCTGCGTGAGGAGCAGAAAGTGCTGTCCCGCCTCGTGGAGTCGCTGAGCACCCAAATCCGGGCCTTGACGGAGCAGCAGGAGCAGCTGCGGGGCCAGCTGCAGGATCTGGACTCCAGGCTCCGTGCTGG
Seq A exon
GAGCTCAGAGTTTGATTCAGAGCACAACCTAACAAGCAATGAAGGGCACAGTCTGAAAAACCTG
Seq C2 exon
GAGCACCGCCTAAATGAGATGGAGAGAACTCAGGCTCAGCTGAGGGATGCTGTCCAGAGCCTGCAGCTTTCTCCAAGGACGCGGGGGTCTTGGAGTCAACCCCAGCCCCTCAAAGCACCCTGCCTCAATGGAGACACCACCTGAGCTGCCCATCCTGCCTCATCACACGTGGTCTGGGAGCAGAGAGATAGCCATCTTAGGGGGGGTGTCTGACTTTGCCTTAGCCCTACTTGGCCTACAGTGGGGAGTGGAGCTGCTGGTCCCAACCACTCTGGCAGTATGAAGTTGCCCAGTAAAATCTTGATTTCAGTGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105122_MULTIEX1-2/2=1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.623 A=1.000 C2=0.932
Domain overlap (PFAM):
C1:
PF041569=IncA=FE(39.7=100),PF154501=DUF4631=FE(46.0=100),PF045827=Reo_sigmaC=FE(45.2=100),PF123293=TMF_DNA_bd=FE(74.3=100)
A:
PF041569=IncA=FE(16.0=100),PF154501=DUF4631=FE(18.6=100),PF045827=Reo_sigmaC=FE(18.3=100),PF123293=TMF_DNA_bd=PD(20.0=63.6)
C2:
PF041569=IncA=PD(38.9=94.4),PF104824=CtIP_N=PD(80.0=96.3),PF060057=DUF904=PD(86.4=94.4),PF123293=TMF_DNA_bd=PD(92.7=94.4)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GAGTCGCTGAGCACCCAAATC
R:
AGCTGAGCCTGAGTTCTCTCC
Band lengths:
133-197
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development