HsaEX0056670 @ hg38
Exon Skipping
Gene
ENSG00000175356 | SCUBE2
Description
signal peptide, CUB domain and EGF like domain containing 2 [Source:HGNC Symbol;Acc:HGNC:30425]
Coordinates
chr11:9050606-9055909:-
Coord C1 exon
chr11:9055793-9055909
Coord A exon
chr11:9053637-9053759
Coord C2 exon
chr11:9050606-9050710
Length
123 bp
Sequences
Splice sites
3' ss Seq
GAGAGTATTTTGTTCCACAGACA
3' ss Score
5.61
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
ATGTGGATGAGTGCTCTTTGGATAGGACCTGTGACCACAGCTGCATCAACCACCCTGGCACATTTGCTTGTGCTTGCAACCGAGGGTACACCCTGTATGGCTTCACCCACTGTGGAG
Seq A exon
ACACCAATGAGTGCAGCATCAACAACGGAGGCTGTCAGCAGGTCTGTGTGAACACAGTGGGCAGCTATGAATGCCAGTGCCACCCTGGGTACAAGCTCCACTGGAATAAAAAAGACTGTGTGG
Seq C2 exon
ATGTCACCACCATCAGGACAAGTGTAACCTTTAAGCTAAATGAAGGCAAGTGTAGTTTGAAAAATGCTGAGCTGTTTCCCGAGGGTCTGCGACCAGCACTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175356_MULTIEX1-2/7=1-5
Average complexity
C2*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.022
Domain overlap (PFAM):
C1:
PF0764510=EGF_CA=PU(92.7=97.4)
A:
PF146701=FXa_inhibition=WD(100=85.7)
C2:
NO
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGGATGAGTGCTCTTTGGA
R:
AGACCCTCGGGAAACAGCTC
Band lengths:
204-327
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development