HsaEX0066764 @ hg19
Exon Skipping
Gene
ENSG00000132958 | TPTE2
Description
transmembrane phosphoinositide 3-phosphatase and tensin homolog 2 [Source:HGNC Symbol;Acc:17299]
Coordinates
chr13:20000565-20006718:-
Coord C1 exon
chr13:20006613-20006718
Coord A exon
chr13:20004608-20004687
Coord C2 exon
chr13:20000565-20000657
Length
80 bp
Sequences
Splice sites
3' ss Seq
ATTTCATTTTGTTGGAACAGGTG
3' ss Score
7.81
5' ss Seq
TCGGTAAGA
5' ss Score
10.53
Exon sequences
Seq C1 exon
AATAGATATGTTGGATATTTTGCACAAGTGAAACATCTCTACAACTGGAATCTCCCTCCAAGACGGATACTCTTTATAAAAAGATTCATTATTTATTCGATTCGTG
Seq A exon
GTGATGTATGTGATCTAAAAGTCCAAGTAGTAATGGAGAAAAAGGTTGTCTTTTCCAGTACTTCATTAGGAAATTGTTCG
Seq C2 exon
ATATTGCATGACATTGAAACAGACAAAATATTAATTAATGTATATGACGGTCCACCTCTGTATGATGATGTGAAAGTGCAGTTTTTCTCTTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000132958-'18-22,'18-21,19-22
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF104094=PTEN_C2=PU(13.0=47.2)
A:
PF104094=PTEN_C2=FE(19.8=100)
C2:
PF104094=PTEN_C2=FE(22.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATGTTGGATATTTTGCACAAGTGA
R:
TCATCATACAGAGGTGGACCGT
Band lengths:
167-247
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)