HsaEX0067836 @ hg38
Exon Skipping
Gene
ENSG00000123607 | TTC21B
Description
tetratricopeptide repeat domain 21B [Source:HGNC Symbol;Acc:HGNC:25660]
Coordinates
chr2:165929650-165931856:-
Coord C1 exon
chr2:165931758-165931856
Coord A exon
chr2:165930172-165930364
Coord C2 exon
chr2:165929650-165929747
Length
193 bp
Sequences
Splice sites
3' ss Seq
TCATTTTTTTTTCTTTTTAGTGT
3' ss Score
11.07
5' ss Seq
TTGGTATGA
5' ss Score
5.24
Exon sequences
Seq C1 exon
GCTTCCACCAAGCTGGAAAACTTGGGAAATACATTGGATGCCATGGAACCACAGAATGCTCAACTTTTCTATAACATTACACTCGCCTTCAGCAGAACT
Seq A exon
TGTGGACGTAGTCAACTTATTCTTCAAAAAATTCAAACGTTACTTGAGAGAGCTTTTAGTTTAAACCCTCAGCAATCAGAATTTGCTACAGAACTTGGATACCAAATGATTTTACAAGGAAGAGTTAAAGAGGCACTGAAGTGGTATAAGACCGCCATGACACTTGATGAGACTAGTGTGTCTGCCCTAGTTG
Seq C2 exon
GATTTATCCAATGTCAGTTGATAGAAGGGCAATTACAGGATGCAGATCAGCAGCTAGAATTTTTAAATGAAATCCAGCAATCCATTGGAAAATCTGCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123607_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.030 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF145591=TPR_19=PU(50.9=44.6)
C2:
PF145591=TPR_19=PD(47.4=81.8)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCACCAAGCTGGAAAACTTGG
R:
CGCAGATTTTCCAATGGATTGCT
Band lengths:
194-387
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development