HsaEX0070589 @ hg19
Exon Skipping
Gene
ENSG00000139722 | VPS37B
Description
vacuolar protein sorting 37 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25754]
Coordinates
chr12:123355437-123380712:-
Coord C1 exon
chr12:123380499-123380712
Coord A exon
chr12:123355759-123355943
Coord C2 exon
chr12:123355437-123355608
Length
185 bp
Sequences
Splice sites
3' ss Seq
CAGATTCTAAATCTTTACAGCTG
3' ss Score
6.3
5' ss Seq
TGGGTCAGT
5' ss Score
4.68
Exon sequences
Seq C1 exon
GTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGGCGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAG
Seq A exon
CTGTTTACTTCTGCAAGCACAATGGCCGTAGTAAGGAATTCAAGTCACAGCGCAGCCGTGGCAGGGAAGGCTCTGCATGGAGTCACAGGACAAAGCCTGTCCTGGAAACGTGCTGGAAGGAAGTCGGCCTCATTCTTTACGACGGGCAGCAGCTCCAAATGAGAAACCAAGGGGCTTGGCTCTGG
Seq C2 exon
ACACAGAATGTTCAGCTTAACAAAGAAATGACACTTGCCAGCAACCGGAGCCTGGCAGAAGGAAACCTTTTGTACCAGCCCCAGCTGGACACGTTGAAAGCACGCTTGACCCAGAAATACCAGGAACTCCAGGTTCTCTTTGAAGCCTATCAGATAAAGAAGACCAAATTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139722_MULTIEX1-1/2=C1-2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.171 A=0.019 C2=0.095
Domain overlap (PFAM):
C1:
PF072008=Mod_r=PU(54.0=73.0),PF0127615=OKR_DC_1=PU(36.0=73.0)
A:
PF072008=Mod_r=PD(42.0=38.9),PF0127615=OKR_DC_1=PD(61.3=85.2)
C2:
PF072008=Mod_r=FE(37.2=100),PF142471=DUF4344=FE(55.6=100)
Other Inclusion Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GCCGAGACGTGGGGATGG
R:
TTTCTGGGTCAAGCGTGCTTT
Band lengths:
242-427
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)