HsaEX0070590 @ hg19
Exon Skipping
Gene
ENSG00000139722 | VPS37B
Description
vacuolar protein sorting 37 homolog B (S. cerevisiae) [Source:HGNC Symbol;Acc:25754]
Coordinates
chr12:123353027-123380712:-
Coord C1 exon
chr12:123380499-123380712
Coord A exon
chr12:123355437-123355608
Coord C2 exon
chr12:123353027-123353109
Length
172 bp
Sequences
Splice sites
3' ss Seq
ATCTTGTGTGTTCCTTGCAGACA
3' ss Score
10.67
5' ss Seq
TAGGTAACT
5' ss Score
6.43
Exon sequences
Seq C1 exon
GTCACGTGTCCCCCCCGCGGGGGGCGGCCCTTGAGGGCGGCGCTTCCGGTCGGCGGAGCCTGGTGGCCGCAGCGGCGGTGGCGACGACGGCCGAGACGTGGGGATGGCGGGCGCCGGGAGCGAAGCCCGGTTCGCCGGGCTGTCGCTGGTGCAGCTCAACGAGCTGCTGGAGGACGAGGGCCAGCTGACGGAGATGGTGCAGAAGATGGAGGAG
Seq A exon
ACACAGAATGTTCAGCTTAACAAAGAAATGACACTTGCCAGCAACCGGAGCCTGGCAGAAGGAAACCTTTTGTACCAGCCCCAGCTGGACACGTTGAAAGCACGCTTGACCCAGAAATACCAGGAACTCCAGGTTCTCTTTGAAGCCTATCAGATAAAGAAGACCAAATTAG
Seq C2 exon
ACAGACAGTCTAGCAGTGCTTCCTTGGAGACCCTGTTAGCACTTCTTCAGGCAGAAGGGGCCAAGATTGAGGAAGACACTGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000139722_MULTIEX1-2/2=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.171 A=0.095 C2=0.107
Domain overlap (PFAM):
C1:
PF072008=Mod_r=PU(54.0=73.0),PF0127615=OKR_DC_1=PU(36.0=73.0)
A:
PF072008=Mod_r=FE(38.0=100)
C2:
PF072008=Mod_r=FE(18.2=100),PF142471=DUF4344=PD(18.2=64.3)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGCCGAGACGTGGGGATG
R:
TCTTCCTCAATCTTGGCCCCT
Band lengths:
202-374
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)