Special

HsaEX0073206 @ hg38

Exon Skipping

Gene
ENSG00000167380 | ZNF226
Description
zinc finger protein 226 [Source:HGNC Symbol;Acc:HGNC:13019]
Coordinates
chr19:44172860-44177687:+
Coord C1 exon
chr19:44172860-44172952
Coord A exon
chr19:44174984-44175171
Coord C2 exon
chr19:44175498-44177687
Length
188 bp
Sequences
Splice sites
3' ss Seq
TAGTTCTTTTTGTATTTCAGATA
3' ss Score
8.44
5' ss Seq
ACTGTGAGC
5' ss Score
4.2
Exon sequences
Seq C1 exon
GGCATCCACCCTTCAAACAAGATGTATCACCTATAGAAAGAAATGAGCAGCTTTGGATAATGACGACAGCAACCCGAAGACAGGGAAATTTAG
Seq A exon
ATACCTTACTTGTAAAAGCTCTTTTGCTCTATGACCTGGCTCAAACTTAAACTTGGATTTGAAGTTAGAAGAAATGTTGGAAGTCATTTATATATGAAGAAATGTTGGAAGGACTCATATATGCATACATTCCTTGAGTGACTATGAATGACTGCCGGGCAGTAACTTCTGGGCTGTGGTTGTAAACT
Seq C2 exon
GAGAGAAAAATCAAAGTAAGTTAATTACTGTTCAAGACAGAGAATCAGAAGAAGAGCTTTCTTGTTGGCAAATCTGGCAACAAATTGCAAATGACTTAACCAGGTGTCAAGACTCCATGATCAATAATTCTCAGTGTCACAAACAAGGTGATTTCCCTTACCAGGTAGGGACAGAACTGTCTATTCAAATTTCTGAAGATGAGAACTATATAGTAAATAAAGCAGATGGTCCCAATAATACTGGGAATCCAGAGTTTCCTATCTTGAGAACCCAGGATTCTTGGAGGAAAACATTCCTGACTGAGTCACAGAGATTGAACAGAGATCAGCAAATTTCCATAAAAAATAAATTATGTCAATGTAAGAAGGGTGTTGATCCCATCGGTTGGATTTCACATCATGATGGTCATAGAGTACACAAAAGTGAAAAATCTTATAGACCCAATGATTATGAAAAAGACAACATGAAGATTTTGACATTTGATCACAATAGCATGATT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000167380_MULTIEX1-9/14=8-10
Average complexity
C1*
Mappability confidence:
99%=100=100%
Protein Impact





	

	
ORF disruption upon sequence inclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.091 A=0.000 C2=0.132
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
PF0135222=KRAB=PD(0.1=0.0)

							
A:
NO

							
C2:
PF134651=zf-H2C2_2=WD(100=3.3),PF134651=zf-H2C2_2=WD(100=3.0),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.4),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.4),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.6),PF134651=zf-H2C2_2=WD(100=3.4)

						

					

				








    
Main Inclusion Isoform:
ENST00000454662fB8075





     
                   









    
Main Skipping Isoform:
ENSP00000336719





     
      









    
Other Inclusion Isoforms:
ENSP00000300823, ENSP00000407474, ENSP00000465401, ENSP00000467003
          









    
Other Skipping Isoforms:
ENSP00000393265, ENSP00000465043, ENSP00000465121, ENSP00000465984, ENSP00000466141, ENSP00000467766, ENSP00000468779
  



Associated events







Other assemblies


hg19




Conservation


Mouse
(mm10)
No conservation detected
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGCATCCACCCTTCAAACAAGA

				
R: 
CCTGGTAAGGGAAATCACCTTGT

				
Band lengths: 
258-446

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • The Cancer Genome Atlas (TCGA)
  • Genotype-Tissue Expression Project (GTEx)
  • Autistic and control brains
  • Pre-implantation embryo development





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