HsaEX1006386 @ hg38
Exon Skipping
Gene
ENSG00000125730 | C3
Description
complement C3 [Source:HGNC Symbol;Acc:HGNC:1318]
Coordinates
chr19:6690629-6693487:-
Coord C1 exon
chr19:6693412-6693487
Coord A exon
chr19:6692924-6693083
Coord C2 exon
chr19:6690629-6690727
Length
160 bp
Sequences
Splice sites
3' ss Seq
ATGCTCTGTGCCCACTCCAGGCT
3' ss Score
6.75
5' ss Seq
ATTGTAAGA
5' ss Score
4.37
Exon sequences
Seq C1 exon
GGTACACCCAGCAGCTGGCCTTCAGACAACCCAGCTCTGCCTTTGCGGCCTTCGTGAAACGGGCACCCAGCACCTG
Seq A exon
GCTGACCGCCTACGTGGTCAAGGTCTTCTCTCTGGCTGTCAACCTCATCGCCATCGACTCCCAAGTCCTCTGCGGGGCTGTTAAATGGCTGATCCTGGAGAAGCAGAAGCCCGACGGGGTCTTCCAGGAGGATGCGCCCGTGATACACCAAGAAATGATT
Seq C2 exon
GGTGGATTACGGAACAACAACGAGAAAGACATGGCCCTCACGGCCTTTGTTCTCATCTCGCTGCAGGAGGCTAAAGATATTTGCGAGGAGCAGGTCAAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000125730-'54-69,'54-68,55-69
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF076789=A2M_comp=FE(10.7=100)
A:
PF076789=A2M_comp=FE(22.6=100)
C2:
PF076789=A2M_comp=PU(27.8=96.4)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGGCCTTCAGACAACC
R:
GCTCCTCGCAAATATCTTTAGCCT
Band lengths:
156-316
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains