HsaEX1023283 @ hg38
Exon Skipping
Gene
ENSG00000175221 | MED16
Description
mediator complex subunit 16 [Source:HGNC Symbol;Acc:HGNC:17556]
Coordinates
chr19:873449-877180:-
Coord C1 exon
chr19:876974-877180
Coord A exon
chr19:875244-875454
Coord C2 exon
chr19:873449-873582
Length
211 bp
Sequences
Splice sites
3' ss Seq
ACCTGGCTTCCTGCCCTCAGGTC
3' ss Score
11.51
5' ss Seq
TCGGTGGGT
5' ss Score
6.9
Exon sequences
Seq C1 exon
CTGAGCGTGCTCCGCCTCTCACCTTCCATGGGCCACCCGCTGGAGGTGGGGCTGGCGCTGCGGCACCTGCTCTTCCTGCTGGAGTACTGCATGGTGACCGGCTACGACTGGTGGGACATCCTGCTGCACGTGCAGCCCAGTATGGTACAGAGCCTGGTGGAGAAGCTGCACGAGGAGTACACGCGCCAGACCGCTGCCCTGCAGCAG
Seq A exon
GTCCTCTCCACCCGGATCCTGGCCATGAAGGCCTCGCTCTGCAAGCTGTCGCCCTGCACGGTGACCCGCGTGTGCGACTACCACACCAAGCTCTTCCTCATCGCCATCAGCTCCACCCTGAAGTCGCTGCTGCGCCCCCACTTTCTCAACACGCCTGACAAGAGCCCCGGCGACCGGCTGACCGAGATCTGCACCAAGATCACCGACGTCG
Seq C2 exon
ACATTGACAAGGTCATGATCAACCTCAAGACGGAGGAATTTGTGCTGGACATGAACACACTGCAGGCGCTGCAGCAGCTCTTGCAGTGGGTGGGCGACTTCGTGCTGTACCTGCTGGCCAGCCTACCCAACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000175221_MULTIEX1-10/15=9-11
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.011 A=0.014 C2=0.000
Domain overlap (PFAM):
C1:
PF116353=Med16=FE(16.9=100)
A:
PF116353=Med16=FE(58.0=100)
C2:
PF116353=Med16=FE(10.8=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTCACCTTCCATGGGCCA
R:
CAGCAGGTACAGCACGAAGTC
Band lengths:
308-519
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains