HsaEX1023464 @ hg38
Exon Skipping
Gene
ENSG00000123600 | METTL8
Description
methyltransferase like 8 [Source:HGNC Symbol;Acc:HGNC:25856]
Coordinates
chr2:171325841-171331867:-
Coord C1 exon
chr2:171331765-171331867
Coord A exon
chr2:171330559-171330698
Coord C2 exon
chr2:171325841-171325906
Length
140 bp
Sequences
Splice sites
3' ss Seq
CTGTTCCTTTATCATGACAGTCA
3' ss Score
6.94
5' ss Seq
CAGGTAAAT
5' ss Score
8.76
Exon sequences
Seq C1 exon
GAACTCTCCGGAGTCCTTTCTGTATTGTTGTGATTTTGCTTCTGGAGCTGTGGAGCTCGTAAAGGTATGCTACTCCTGGGAATCATACCAACTGATGCCTAAG
Seq A exon
TCACACTCGTCCTACAGAGCAACCCAGTGTTTTGCCTTTGTTCATGATGTATGTGATGATGGCTTACCTTACCCTTTTCCAGATGGGATCCTGGATGTCATTCTCCTTGTCTTTGTGCTCTCTTCTATTCATCCTGACAG
Seq C2 exon
GACATTGTTTATCTGAAAATTTTTATGTTCGAGGAGATGGTACCAGAGCATATTTCTTTACAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000123600_MULTIEX1-7/10=6-10
Average complexity
C1*
Mappability confidence:
100%=100=80%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF134891=Methyltransf_23=FE(17.7=100)
A:
PF082427=Methyltransf_12=FE(43.8=100)
C2:
PF136491=Methyltransf_25=PD(2.2=33.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTCTCCGGAGTCCTTTCTGTA
R:
TGTAAAGAAATATGCTCTGGTACCA
Band lengths:
162-302
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains