HsaEX1036666 @ hg38
Exon Skipping
Gene
ENSG00000107290 | SETX
Description
senataxin [Source:HGNC Symbol;Acc:HGNC:445]
Coordinates
chr9:132271710-132275420:-
Coord C1 exon
chr9:132275256-132275420
Coord A exon
chr9:132274556-132274858
Coord C2 exon
chr9:132271710-132271808
Length
303 bp
Sequences
Splice sites
3' ss Seq
TTGTTTCCTTCTTACCTCAGCAG
3' ss Score
6.11
5' ss Seq
GAGGTAGGT
5' ss Score
9.65
Exon sequences
Seq C1 exon
CTCATATATAAATGTTCAAGAAATAAAACTGGTGATGGAAATAATTAAGCTTATTAAAGACAAAAGAAAGGATGTTAGTTTTCGAAACATTGGCATAATAACTCATTACAAGGCCCAGAAGACGATGATTCAGAAGGATTTGGACAAAGAGTTCGATAGAAAAGG
Seq A exon
CAGTAAAATTAAAGATTAAATATTGGAGATCCATAACCTTAAAATCATCTTAACTTAGAAGCACACAGACTACCAAAATCGAATCTAGAAAACAATAGAAAATCAGACCTGTAGGCTGGGTGTGGTGGCTCACACCTGTAATCCCAGCACTTTGGGAGGCTGAGGCGGGCAGATCACCTGAGGTCAGGAGGTTGAGACCAGCCTGGGCAACATGGTGAAACCCCATCTCTACTGAAAAAAAATACAAAAATTAGCCAGGCGTGGTGGCGCGCTCCCGTAGTCCCTGCTACTCGGAAGGCTGAG
Seq C2 exon
ACCAGCAGAAGTAGACACTGTGGATGCATTCCAGGGTCGGCAGAAGGATTGTGTTATTGTTACGTGTGTCAGAGCAAATAGCATCCAAGGTTCAATTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107290_MULTIEX3-2/4=1-3
Average complexity
S*
Mappability confidence:
80%=100=80%
Protein Impact
ORF disruption upon sequence inclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF130871=AAA_12=FE(27.2=100)
A:
PF130871=AAA_12=PD(2.7=57.1)
C2:
PF130871=AAA_12=FE(16.3=100)
Main Inclusion Isoform:
ENST00000224140fB25551
Other Inclusion Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Rat
(rn6)
No conservation detected
Cow
(bosTau6)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGTTCAAGAAATAAAACTGGTGATGG
R:
TGAACCTTGGATGCTATTTGCTCT
Band lengths:
247-550
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains