Special

HsaEX1046511 @ hg38

Exon Skipping

Gene
ENSG00000182903 | ZNF721
Description
zinc finger protein 721 [Source:HGNC Symbol;Acc:HGNC:29425]
Coordinates
chr4:439988-474142:-
Coord C1 exon
chr4:473981-474142
Coord A exon
chr4:472575-472701
Coord C2 exon
chr4:439988-444432
Length
127 bp
Sequences
Splice sites
3' ss Seq
TGATACATATGTATTTTCAGGAA
3' ss Score
8.2
5' ss Seq
TAGGTGAGG
5' ss Score
7.65
Exon sequences
Seq C1 exon
GTTGCTTCAGCCTGAGCTCGGTTAGGGCCTCACTTCCCTGCTTCCACACCTCAGGGAGGCCTCGGTGATTTTGCCAGAGCCTCAGCCTCCATCGCTCTGTAACCTGCGGGTATTGGATGATTCGTAGCTAAGACTTCGCGACACCCTTGAAGCTGAGAAATG
Seq A exon
GAACCCTTAACATTCAGGGATGTGGCCATAGAATTCTCTCCAGAAGAGTGGAAATGCCTGGACCCTGCCCAGCAGAATTTGTATAGAGATGTGATGTTGGAGAACTACAGAAACCTGGTCTCCCTAG
Seq C2 exon
CTATGTGTTCTCATTTCACCCAAGACTTTTTGCCAGTGCAGGGGATAGAAGATTCATTCCACAAACTTATACTGAGAAGATATGAGAAATGTGGGCATGATAATTTACAATTAAGGAAAGGCTGTAAAAGTATGAACGTGTGTAAAGTGCAGAAGGGAGTTTATAATGGAATTAATAAATGCTTGTCAAATACTCAGAGCAAAATATTTCAATGTAATGCACGTGTCAAAGTTTTTAGTAAATTTGCAAATTCAAACAAAGATAAGACAAGACATACTGGAGAGAAACACTTTAAATGTAACGAATGTGGCAAGTCATTTCAGAAGTTCTCAGACCTAACTCAACATAAAGGAATTCATGCTGGAGAGAAACCCTACACTTGTGAAGAACGTGGCAAAGACTTTGGATGGTACACAGACCTGAATCAACACAAGAAAATTCATACTGGAGAGAAACCTTACAAATGTGAAGAATGTGGCAAAGCCTTTAATAGGTCAACA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000182903_MULTIEX1-6/14=4-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact





	

	
ORF disruption upon sequence exclusion





No structure available

		

			
Features


			

				
Disorder rate (Iupred):
  C1=0.158 A=0.008 C2=0.035
 
                        

				
Domain overlap (PFAM):

					





						

							
C1:
NO

							
A:
PF0135222=KRAB=WD(100=95.3)

							
C2:
PF139121=zf-C2H2_6=WD(100=2.6),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.4),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.9),PF134651=zf-H2C2_2=WD(100=2.7),PF134651=zf-H2C2_2=WD(100=2.9)

						

					

				








    
Main Inclusion Isoform:
ENSP00000428878





     
                   









    
Main Skipping Isoform:
ENST00000506646fB30927





     
      









    
Other Inclusion Isoforms:
ENSP00000421325, ENSP00000423586, ENSP00000430163
          









    
Other Skipping Isoforms:
NA
  



Associated events







Conservation


Mouse
(mm10)
chr17:22687723-22687849 
Mouse
(mm9)
No conservation detected
Rat
(rn6)
chr6:143909822-143909948 
HIGH PSI
RnoEX0101344
(Zfp386)
Cow
(bosTau6)
No conservation detected
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected




Primers PCR

	

		

			
Suggestions for RT-PCR validation

			

				
F: 
GGTGATTTTGCCAGAGCCTCA

				
R: 
CCCTTCTGCACTTTACACACGT

				
Band lengths: 
256-383

			

		

	





	
Functional annotations
(Submit an annotation)

	


There are 0 annotated functions for this event 


		










GENOMIC CONTEXT[edit]












INCLUSION PATTERN[edit]






SPECIAL DATASETS
  • Autistic and control brains





Retrieved from "https://vastdb.crg.eu/wiki/Special:VastDB"