HsaEX6004751 @ hg38
Exon Skipping
Gene
ENSG00000166682 | TMPRSS5
Description
transmembrane protease, serine 5 [Source:HGNC Symbol;Acc:HGNC:14908]
Coordinates
chr11:113690841-113694640:-
Coord C1 exon
chr11:113694478-113694640
Coord A exon
chr11:113693071-113693249
Coord C2 exon
chr11:113690841-113690939
Length
179 bp
Sequences
Splice sites
3' ss Seq
AGCATGGCCCCTGTGTGCAGTTT
3' ss Score
4.41
5' ss Seq
CAGGTGCGG
5' ss Score
9.13
Exon sequences
Seq C1 exon
AGTGTGGAGCGAGGCCCCTGGCTTCCCGGATAGTTGGTGGGCAGTCTGTGGCTCCTGGGCGCTGGCCGTGGCAGGCCAGCGTGGCCCTGGGCTTCCGGCACACGTGTGGGGGCTCTGTGCTAGCGCCACGCTGGGTGGTGACTGCTGCACATTGTATGCACAG
Seq A exon
TTTCAGGCTGGCCCGCCTGTCCAGCTGGCGGGTTCATGCGGGGCTGGTCAGCCACAGTGCCGTCAGGCCCCACCAAGGGGCTCTGGTGGAGAGGATTATCCCACACCCCCTCTACAGTGCCCAGAATCATGACTACGACGTCGCCCTCCTGAGGCTCCAGACCGCTCTCAACTTCTCAG
Seq C2 exon
ACACTGTGGGCGCTGTGTGCCTGCCGGCCAAGGAACAGCATTTTCCGAAGGGCTCGCGGTGCTGGGTGTCTGGCTGGGGCCACACCCACCCTAGCCATA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166682-'11-18,'11-14,16-18
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.023 C2=0.000
Domain overlap (PFAM):
C1:
PF154941=SRCR_2=PD(5.1=9.1),PF0008921=Trypsin=PU(19.0=80.0)
A:
PF154941=SRCR_2=PD(9.3=13.1),PF0008921=Trypsin=PU(30.6=91.8)
C2:
PF0008921=Trypsin=FE(14.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTGGCTTCCCGGATAGTTGGT
R:
TATGGCTAGGGTGGGTGTGG
Band lengths:
245-424
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains