HsaEX6005719 @ hg19
Exon Skipping
Gene
ENSG00000166157 | TPTE
Description
transmembrane phosphatase with tensin homology [Source:HGNC Symbol;Acc:12023]
Coordinates
chr21:10910307-10916475:-
Coord C1 exon
chr21:10916370-10916475
Coord A exon
chr21:10914363-10914442
Coord C2 exon
chr21:10910307-10910399
Length
80 bp
Sequences
Splice sites
3' ss Seq
ATTTCATTTTGTTGGAACAGGTT
3' ss Score
7.3
5' ss Seq
TCGGTAAGA
5' ss Score
10.53
Exon sequences
Seq C1 exon
AAGAGATATGTTGCATATTTTGCACAAGTGAAACATCTCTACAACTGGAATCTCCCTCCAAGACGGATACTCTTTATAAAACACTTCATTATTTATTCGATTCCTC
Seq A exon
GTTATGTACGTGATCTAAAAATCCAAATAGAAATGGAGAAAAAGGTTGTCTTTTCCACTATTTCATTAGGAAAATGTTCG
Seq C2 exon
GTACTTGATAACATTACAACAGACAAAATATTAATTGATGTATTCGACGGTCTACCTCTGTATGATGATGTGAAAGTGCAGTTTTTCTATTCG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000166157-'32-36,'32-35,33-36=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF104094=PTEN_C2=PU(13.0=47.2)
A:
PF104094=PTEN_C2=FE(19.8=100)
C2:
PF104094=PTEN_C2=FE(22.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCACAAGTGAAACATCTCTACA
R:
ACTGCACTTTCACATCATCATACAGA
Band lengths:
168-248
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)