HsaEX6007341 @ hg19
Exon Skipping
Gene
ENSG00000105855 | ITGB8
Description
integrin, beta 8 [Source:HGNC Symbol;Acc:6163]
Coordinates
chr7:20370725-20406809:+
Coord C1 exon
chr7:20370725-20371556
Coord A exon
chr7:20403260-20403345
Coord C2 exon
chr7:20406635-20406809
Length
86 bp
Sequences
Splice sites
3' ss Seq
TGTTTTCTCCTTCATTGCAGAAG
3' ss Score
9.95
5' ss Seq
GAGGTGTGC
5' ss Score
5.35
Exon sequences
Seq C1 exon
TATGCAGCAGAAGCCCCACCGGCTGGAGAGAAACAAAAGCTCTTTTCTTTGTCCCGGAGCAGGCTGCGGAGCCCTTGCAGAGCCCTCTCTCCAGTCGCCGCCGGGGCCCTTGGCCGTCGAAGGAGGTGCTTCTCGCGGAGACCGCGGGACCCGCCGTGCCGAGCCGGGAGGGCCGCAGGGGCCCTGAGATGCCGAGCGGTGCCCGGGCCCGCTTACCTGCACCGCTTGCTCCGAGCCGCGGGGTCCGCCTGCTAGGCCTGCGGAAAACGTCCTAGCGACACTCGGCCCGCGGGCCCCGAGGTGCGCCCGGGAGGCGCGAGCCCGCGTCCGGAAGGCAGTCAGGCGGCGGGCGCGGGGCGGGCTGTTTTGCATTATGTGCGGCTCGGCCCTGGCTTTTTTTACCGCTGCATTTGTCTGCCTGCAAAACGACCGGCGAGGTCCCGCCTCGTTCCTCTGGGCAGCCTGGGTGTTTTCACTTGTTCTTGGACTGGGCCAAGGTG
Seq A exon
AAGACAATAGATGTGCATCTTCAAATGCAGCATCCTGTGCCAGGTGCCTTGCGCTGGGTCCAGAATGTGGATGGTGTGTTCAAGAG
Seq C2 exon
GATTTCATTTCAGGTGGATCAAGAAGTGAACGTTGTGATATTGTTTCCAATTTAATAAGCAAAGGCTGCTCAGTTGATTCAATAGAATACCCATCTGTGCATGTTATAATACCCACTGAAAATGAAATTAATACCCAGGTGACACCAGGAGAAGTGTCTATCCAGCTGCGTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000105855-'0-7,'0-5,6-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.062 C2=0.034
Domain overlap (PFAM):
C1:
NO
A:
PF0036213=Integrin_beta=PU(4.1=58.6)
C2:
PF0036213=Integrin_beta=FE(13.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTGTTCTTGGACTGGGCCAAG
R:
ACACTTCTCCTGGTGTCACCT
Band lengths:
181-267
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)