MmuEX0024693 @ mm10
Exon Skipping
Gene
ENSMUSG00000025321 | Itgb8
Description
integrin beta 8 [Source:MGI Symbol;Acc:MGI:1338035]
Coordinates
chr12:119202407-119238802:-
Coord C1 exon
chr12:119237672-119238802
Coord A exon
chr12:119208519-119208604
Coord C2 exon
chr12:119202407-119202581
Length
86 bp
Sequences
Splice sites
3' ss Seq
CATCTTAACTTGAATTTCAGAAC
3' ss Score
6.45
5' ss Seq
GAGGTGTGT
5' ss Score
6.14
Exon sequences
Seq C1 exon
CTAAGCTGATTTATGCAGCAGAGCCCCATCGGCTGGGGAGAAACAAAAGCTCTTTTCTTTGTCTGGGAGCGGACTGTGGAGCCCGTACTTGCTTCGCCCCCGCGGGCCATCGGCTGTCCAAGGAGGTGCTTTTTGTTGAGACTGCAAGCCCCGCCGTGCGGAGCTGGGAGGGCCTTAAGGGCCCTGAGATGCAGAGAGCTGCCCTGGACCGAATACCTGTATCGCCTACTGAGAGCAACTGGGTCGGCCAACCCGGCCTGTCGAAAAGGTCCTAGGGACTCGCAGCCCACGGGCCTCAAGGTGCGCTCTCAAGTCGGGAGAGCGCATCAGGAAAGCAACTAGGCAGTAGGCACCGGGCGGGCTGCTTTGCATTATGTGCGGCTCGGCCCTGGCTTTTCTGACTGCTGCACTGCTCTCTCTGCACAACTGCCAGCGAGGTCCAGCCTTGGTTCTTGGGGCAGCCTGGGTATTTTCACTTGTTCTCGGACTGGGCCAAAGTG
Seq A exon
AACACAATAGATGTGGCTCTGCAAATGTGGTCTCCTGTGCCAGGTGCCTCCAGCTGGGTCCGGAATGCGGATGGTGTGTTCAAGAG
Seq C2 exon
GATTTTGTTTCAGGTGGATCAGGAAGTGAACGTTGTGATACTGTTTCCAGTTTGATAAGCAAAGGCTGTCCAGTTGATTCAATAGAATACCTGTCTGTGCATGTTGTAACGTCAAGTGAGAATGAAATCAATACCCAGGTGACACCGGGAGAAGTCTCAGTCCAACTGCATCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000025321_CASSETTE4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.034
Domain overlap (PFAM):
C1:
NO
A:
PF0036213=Integrin_beta=PU(4.1=58.6)
C2:
PF0036213=Integrin_beta=FE(13.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGGGCTGCTTTGCATTATGTG
R:
ACGTTCACTTCCTGATCCACC
Band lengths:
176-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types